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Merck

CANPIT-96K

MILLIPLEX® Canine Pituitary Expanded Panel

Configurable Canine Pituitary Expanded 6-Plex Panel

Synonym(s):

canine endocrine biomarker set, canine endocrine function markers, canine endocrine research tool, canine hormonal profiling solution, canine hormone detection kit, canine pituitary hormone assay, canine pituitary hormone profile, dog hormone analysis kit, dog pituitary hormone multiplex, pituitary hormone biomarker panel for dogs

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000
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Product Name

MILLIPLEX® Canine Pituitary Expanded Panel, Configurable Canine Pituitary Expanded 6-Plex Panel

quality

100

species reactivity

canine

manufacturer/tradename

Milliplex®

packaging

1 ea of

assay range

accuracy: 92%
(TSH)

accuracy: 95%
(GH)

sensitivity: 0.01 ng/mL
(GH)

sensitivity: 0.09 ng/mL
(LH)

sensitivity: 1.21 ng/mL
(FSH)

sensitivity: 1.62 ng/mL
(TSH)

sensitivity: 2.45 ng/mL
(Prolactin)

sensitivity: 2.45 pg/mL
(ACTH)

standard curve range: 0.01-50 ng/mL
(GH)

standard curve range: 0.1-350 ng/mL
(LH)

standard curve range: 0.9-3,750 ng/mL
(TSH)

standard curve range: 1.7-7,000 ng/mL
(Prolactin)

standard curve range: 2.4-10,000 ng/mL
(FSH)

standard curve range: 2.4-10,000 pg/mL
(ACTH)

inter-assay cv: <20%
intra-assay cv: <10%

technique(s)

multiplexing: suitable

input

serum plasma
serum plasma

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Biochem/physiol Actions

Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel except for canine LH having ~5% cross-reactivity with the TSH antibody pair.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

General description

Called the “master gland” because it controls many other endocrine glands, the pituitary gland secretes key hormones that play important roles in the regulation of metabolism, growth, and reproduction. The Canine Pituitary Expanded Panel thus enables you to focus on the therapeutic potential of reproduction, growth, metabolic homeostasis, and pituitary related diseases such as acromegaly, growth hormone deficiency, diabetes insipidus and pituitary tumors.

MILLIPLEX® Canine Pituitary Expanded Panel is a 6-plex kit to be used for the quantification of any or all of the following analytes: Adrenocorticotropic Hormone (ACTH), Growth Hormone (GH), Follicle-Stimulating Hormone (FSH), Luteinizing Hormone (LH), Prolactin, and Thyroid-Stimulating Hormone (TSH). This kit may be used for the analysis of pituitary hormones in canine serum or plasma, canine tissue extract, or cell/tissue supernatant samples. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Endocrine
Hormonal regulation in dogs involves a complex interplay between the hypothalamus and pituitary gland. Biomarkers such as ACTH, FSH, GH, LH, Prolactin, and TSH provide critical insights into this axis. ACTH reflects adrenal stimulation and stress response, while FSH and LH are key regulators of reproductive function. GH influences growth and metabolism, Prolactin supports lactation and immune modulation, and TSH controls thyroid hormone production. Together, these analytes offer a comprehensive view of endocrine health and are essential for studying hormonal imbalances and pituitary-related disorders in canine models.

Other Notes

Replaces: This panel replaces CPTMAG-96K.

Preparation Note

Recommended storage for kit components is 2 - 8°C.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Features and Benefits

Features:
  • Targets six key pituitary hormones involved in canine endocrine regulation
  • Includes ACTH, FSH, GH, LH, Prolactin, and TSH for comprehensive profiling
  • Multiplex format enables simultaneous detection of multiple analytes
  • Compatible with canine serum, plasma, tissue extracts, and supernatants
  • Designed for research into pituitary function, growth, reproduction, and metabolism
Benefits:
  • Provides sensitive and specific measurement of pituitary hormone levels
  • Supports investigation of endocrine disorders and pituitary-related diseases
  • Facilitates evaluation of therapeutic interventions in canine models
  • Enables efficient use of limited samples with high-throughput capability
  • Delivers reproducible results with built-in controls and optimized reagents

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 6 analytes in canine serum, plasma, tissue extracts, or cell culture supernatants.

Analytes included: ACTH, FSH, GH, LH, Prolactin, TSH

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

10 - Combustible liquids

wgk

WGK 3


Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
CANPIT-96K-0404054839754463
CANPIT-96K-0204054839754449
CANPIT-96K-0504054839754470
CANPIT-96K-0604054839754487
CANPIT-96K-0304054839754456
CANPIT-96K-0104054839754432

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