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Merck

HCVD3MAG-67K

MILLIPLEX® Human Cardiovascular Disease Panel

Configurable Human CVD (Acute Phase) 10-Plex Panel 3

Synonym(s):

human CVD APP immunoassay panel, luminex human cardiovascular disease acute phase proteins multiplex assay, millipore human CVD acute phase proteins multiplex kit, CVD assay snapshot, CVD detection kit, CVD multiplex product sheet, cardiovascular biomarker listing, cardiovascular biomarker profile, human CVD assay overview, human cardiovascular panel summary, human inflammation product info, human vascular health research tool, vascular inflammation biomarker panel

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Key Documents

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Product Name

MILLIPLEX® Human Cardiovascular Disease Panel, Configurable Human CVD (Acute Phase) 10-Plex Panel 3

species reactivity

human

manufacturer/tradename

Milliplex®

Quality Level

200

packaging

1 ea of

assay range

accuracy: 102%
(Haptoglobin)
accuracy: 109%
(AGP)
accuracy: 113%
(Platelet Factor-4)
accuracy: 117%
(Adipsin)
standard curve range: 0.004-15 ng/mL
(L-Selectin & SAP)
standard curve range: 0.012-50 ng/mL
(CRP)
standard curve range: 0.037-150 ng/mL
(PF4)
standard curve range: 0.061-250 ng/mL
(HPTGN)
standard curve range: 0.098-400 ng/mL
(AGP & Adipsin)
standard curve range: 0.244-1,000 ng/mL
(Fetuin A & vWF)
standard curve range: 0.488-2,000 ng/mL
(A2M)

technique(s)

multiplexing: suitable

input

serum plasma (Cell culture, cell culture supernatants)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:
  • Targets key biomarkers involved in cardiovascular inflammation, coagulation, and immune response
  • Includes 10 analytes relevant to vascular health, acute-phase response, and metabolic regulation
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with human serum and plasma samples
  • Designed for research in cardiovascular disease, systemic inflammation, and metabolic disorders
Benefits:
  • Provides a comprehensive profile of cardiovascular and inflammatory biomarkers
  • Supports investigation of disease mechanisms in atherosclerosis, thrombosis, and vascular inflammation
  • Facilitates evaluation of therapeutic interventions targeting cardiovascular risk pathways
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for translational and clinical research

General description

Cardiovascular disease is driven by a complex interplay of inflammation, coagulation, lipid metabolism, and immune response. This set of biomarkers—α-1-Acid Glycoprotein (AGP), α-2-Macroglobulin, Adipsin/Factor D, CRP, Fetuin A, Fibrinogen, Haptoglobin, sL-Selectin, Platelet Factor 4 (PF4)/CXCL4, and Serum Amyloid P (SAP)—captures key physiological processes associated with cardiovascular risk and progression. These analytes are involved in acute-phase response, vascular inflammation, platelet activation, and metabolic regulation, making them highly relevant for research in atherosclerosis, thrombosis, and systemic inflammation.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 10 analytes in human serum, plasma, or cell culture supernatants.

Analytes included: α-1-Acid Glycoprotein (AGP), α-2-Macroglobulin, Adipsin/Factor D, CRP, Fetuin A, Fibrinogen, Haptoglobin, sL-Selectin, Platelet Factor 4 (PF4)/CXCL4, Serum Amyloid P (SAP)

Note: Fibrinogen cannot be measured in serum samples.Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificates of Analysis (COA)

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Coagulation factors, fibrinogen and plasminogen activator inhibitor-1, are differentially regulated by yellow fever virus infection of hepatocytes.
Woodson, SE; Freiberg, AN; Holbrook, MR
Virus Research null
Rima Habre et al.
Environment international, 118, 48-59 (2018-05-26)
Exposure to ultrafine particles (UFP, particles with aerodynamic diameter < 100 nm) is associated with reduced lung function and airway inflammation in individuals with asthma. Recently, elevated UFP number concentrations (PN) from aircraft landing and takeoff activity were identified downwind of the Los
Daniel O'Connor et al.
Molecular systems biology, 16(11), e9888-e9888 (2020-11-20)
Neisseria meningitidis is a major cause of meningitis and septicaemia. A MenB vaccine (4CMenB) was licensed by the European Medicines Agency in January 2013. Here we describe the blood transcriptome and proteome following infant immunisations with or without concomitant 4CMenB
Nguyen Lam Vuong et al.
eLife, 10 (2021-06-23)
Early identification of severe dengue patients is important regarding patient management and resource allocation. We investigated the association of 10 biomarkers (VCAM-1, SDC-1, Ang-2, IL-8, IP-10, IL-1RA, sCD163, sTREM-1, ferritin, CRP) with the development of severe/moderate dengue (S/MD). We performed
Anna C Belkina et al.
Frontiers in immunology, 9, 2783-2783 (2018-12-21)
Even with effective viral control, HIV-infected individuals are at a higher risk for morbidities associated with older age than the general population, and these serious non-AIDS events (SNAEs) track with plasma inflammatory and coagulation markers. The cell subsets driving inflammation
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Global Trade Item Number

SKUGTIN
HCVD3MAG-67K-0104053252798900
HCVD3MAG-67K-0404053252798931
HCVD3MAG-67K-0704053252798962
HCVD3MAG-67K-0604053252798955
HCVD3MAG-67K-0504053252798948
HCVD3MAG-67K-0904053252798986
HCVD3MAG-67K-0304053252798924
HCVD3MAG-67K-1004053252799495
HCVD3MAG-67K-0804053252798979
HCVD3MAG-67K-0204053252798917

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