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Merck

HCVD4MAG-67K

MILLIPLEX® Human Cardiovascular Disease Panel

Configurable Human CVD 7-Plex Panel 4

Synonym(s):

human CVD immunoassay panel, luminex human cardiovascular disease multiplex assay, millipore human CVD multiplex kit, CVD assay snapshot, CVD multiplex product sheet, cardiac injury detection kit, cardiovascular biomarker listing, endothelial activation biomarker panel, human CVD assay overview, human cardiovascular panel summary, human vascular health research tool, vascular biomarker profile, vascular inflammation product info

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Key Documents

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Product Name

MILLIPLEX® Human Cardiovascular Disease Panel, Configurable Human CVD 7-Plex Panel 4

species reactivity

human

manufacturer/tradename

Milliplex®

Quality Level

200

packaging

1 ea of

assay range

accuracy: 103%
(Thrombomodulin)
accuracy: 104%
(Pentraxin-3 (PTX3))
accuracy: 104%
(Tissue Factor (TF))
accuracy: 106%
(Pecam-1)
accuracy: 109%
(sE-Selectin)
standard curve range: 0.01-5 ng/mL
(Troponin T (TnT))
standard curve range: 0.04-30 ng/mL
(Follistatin (FST))
standard curve range: 0.14-100 ng/mL
(Pentraxin-3 (PTX3) & Tissue Factor (TF))
standard curve range: 0.27-200 ng/mL
(Pecam-1)
standard curve range: 0.34-250 ng/mL
(Thrombomodulin)
standard curve range: 2.7-2,000 ng/mL
(sE-Selectin)
inter-assay cv: <20%
intra-assay cv: <10%

technique(s)

multiplexing: suitable

input

serum plasma (Cell culture, cell culture supernatants)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

Biochem/physiol Actions

Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:
  • Targets biomarkers involved in endothelial activation, coagulation, and cardiac injury
  • Includes 7 analytes relevant to vascular health, inflammation, and myocardial damage
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with human serum and plasma samples
  • Designed for research in cardiovascular disease, thrombosis, and vascular inflammation
Benefits:
  • Provides a focused profile of vascular and cardiac biomarkers
  • Supports investigation of endothelial dysfunction and myocardial injury mechanisms
  • Facilitates evaluation of therapeutic interventions and cardiovascular risk assessment
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for translational and clinical research

General description

Endothelial dysfunction and vascular inflammation are central to the development and progression of cardiovascular disease. This set of biomarkers—sCD31/sPECAM-1, sE-Selectin, Follistatin (FST), Pentraxin-3 (PTX3), Thrombomodulin, Tissue Factor (TF), and Troponin T (TnT)—captures key indicators of endothelial activation, coagulation, and cardiac injury. These analytes are valuable for studying vascular remodeling, atherosclerosis, and acute coronary syndromes, supporting both translational and clinical cardiovascular research.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in human serum, plasma, or cell culture supernatants.

Analytes included: sCD31/sPECAM-1, sE-Selectin, Follistatin (FST), Pentraxin-3 (PTX3), Thrombomodulin, Tissue Factor (TF), Troponin T (TnT)

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificates of Analysis (COA)

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Lauren L Ching et al.
Frontiers in pediatrics, 8, 295-295 (2020-07-17)
Kawasaki disease (KD) is the leading cause of acquired pediatric heart disease in the developed world as 25-30% of untreated patients and at least 5% of treated patients will develop irreversible coronary artery lesions (CAL). Pentraxin-3 (PTX-3) has been well-studied
Kévin Contrepois et al.
Cell, 181(5), 1112-1130 (2020-05-30)
Acute physical activity leads to several changes in metabolic, cardiovascular, and immune pathways. Although studies have examined selected changes in these pathways, the system-wide molecular response to an acute bout of exercise has not been fully characterized. We performed longitudinal
Miša Korva et al.
Viruses, 11(8) (2019-07-31)
Hemorrhagic fever with renal syndrome (HFRS) and Crimean-Congo hemorrhagic fever (CCHF) are important viral hemorrhagic fevers (VHF), especially in the Balkan region. Infections with Dobrava or Puumala orthohantavirus and Crimean-Congo hemorrhagic fever orthonairovirus can vary from a mild, nonspecific febrile

Global Trade Item Number

SKUGTIN
HCVD4MAG-67K-0204053252798320
HCVD4MAG-67K-0104053252798313
HCVD4MAG-67K-0504053252798351
HCVD4MAG-67K-0404053252798344
HCVD4MAG-67K-0704053252798375
HCVD4MAG-67K-0804053252798382
HCVD4MAG-67K-0304053252798337
HCVD4MAG-67K-0604053252798368

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