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ABC95 Anti-Praf2 (JM4) Antibody

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ABC95
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IHCRbSerumPolyclonal Antibody
      Description
      Catalogue NumberABC95
      DescriptionAnti-Praf2 (JM4) Antibody
      Alternate Names
      • PRA1 family protein 2
      • Prenylated Rab acceptor 1 family protein 2
      • PRAF2
      • JM4
      Background InformationPrenylated Rab acceptor 1 family protein 2 (PRAF2), or JM4, is a novel 19-kDa transmembrane protein belonging to the PRA1 family. It is highly expressed in the brain, and has been shown to be enriched in synaptic vesicles. PRAF2 is also relatively abundant in the spleen, small intestine, lung, pancreas, as well as various tumors affecting the ovary, breast, and colon. Recent studies have identified PRAF2 as a potential marker for neuroblastoma. Like other PRAF1 proteins, it is localized to the golgi, endoplasmic reticulum, and vesicular structures. The precise role of PRAF2 is not yet clear, but studies suggest that it may play a role in cellular transport processes.
      References
      Product Information
      FormatSerum
      Control
      • SK-N-SH cell lysate
      PresentationRabbit polyclonal serum containing with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Praf2 (JM4) Antibody is an antibody against Praf2 (JM4) for use in Western Blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A representative lot detected Praf2 (JM4) in mouse and human cerebellum tissue and in human breast cancer tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Praf2 (JM4).
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteDemonstrated to react with Human, Mouse, and Rat. Predicted to react with Guinea Pig, Horse, Cow, Dog, and Hamster based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PRAF2
      • JM4
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~18 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceWestern Blot Analysis: A 1:2,000 dilution from a representative lot detected Praf2 (JM4) in 10 µg of SK-N-SH cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABC95 04053252599972

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies