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Merck

405655

2-Hydroxy-2-methylpropiophenone

97%

Synonym(s):

1-Hydroxy-1-methylethyl phenyl ketone, 1-Phenyl-2-methyl-2-hydroxypropanone, 2-Hydroxy-2-methyl-1-phenyl-1-propanone, 2-Methyl-3-phenyl-3-oxopropan-2-ol

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About This Item

Linear Formula:
C6H5COC(CH3)2OH
CAS Number:
7473-98-5
Molecular Weight:
164.20
NACRES:
NA.23
PubChem Substance ID:
24865322
UNSPSC Code:
12162002
EC Number:
231-272-0
MDL number:
MFCD00040710

Key Documents

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InChI key

XMLYCEVDHLAQEL-UHFFFAOYSA-N

InChI

1S/C10H12O2/c1-10(2,12)9(11)8-6-4-3-5-7-8/h3-7,12H,1-2H3

SMILES string

CC(C)(O)C(=O)c1ccccc1

assay

97%

form

liquid

refractive index

n20/D 1.533 (lit.)

bp

102-103 °C/4 mmHg (lit.)

density

1.077 g/mL at 25 °C (lit.)

Quality Level

200

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General description

2-Hydroxy-2-methylpropiophenone is a radical photoinitiator (PI) molecule that can be used in the crosslinking of polymers by the exposure of UV radiation. It can be used in the development of UV curable resins for exterior coating applications.

Application

  • Photochemical Thiol-Ene “Click” Chemistry: The study utilized 2-hydroxy-2-methylpropiophenone for the synthesis of highly functional polyols by photochemical thiol-ene “click” chemistry (M Ionescu, A Garcia-Comer, T Spidel, 2023).
  • Development of Water-Soluble Type I Photoinitiators: This study focused on the development of new water-soluble type I photoinitiators for hydrogel synthesis using 2-hydroxy-2-methylpropiophenone, enhancing the understanding of photopolymerization processes (B Aubry, F Dumur, M Lansalot, E Bourgeat-Lami, 2022).

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H412

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

251.6 °F - closed cup

flash_point_c

122 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ9517
0000499839
0000499839
MKCX8496
0000408730

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Anirudha Banerjee et al.
Science advances, 5(8), eaax1893-eaax1893 (2019-08-28)
Structures and particles that slowly release solute into solution can attract or repel other particles in suspension via diffusiophoresis, a process we termed "soluto-inertial (SI) interactions." These SI interactions involve "beacons" that establish and sustain nonequilibrium solute fluxes over long
Lu Li et al.
Polymers, 12(1) (2020-01-18)
The detection of p-nitrophenol (PNP) is of great significance for assessment of environment pollution and potential health risks. In this study, based on inverse opal polymeric photonic crystals (IOPPCs), a selective and visual sensor for high-performance PNP detection is developed.
Xuehua Zhang et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(30), 9253-9257 (2015-07-15)
Nanodroplets on a solid surface (i.e., surface nanodroplets) have practical implications for high-throughput chemical and biological analysis, lubrications, laboratory-on-chip devices, and near-field imaging techniques. Oil nanodroplets can be produced on a solid-liquid interface in a simple step of solvent exchange
Photopatternable conductive PDMS materials for microfabrication
Cong H and Pan T
Advances in Functional Materials, 18(13), 1912-1921 (2008)
Martin F Haase et al.
Nature communications, 8(1), 1234-1234 (2017-11-02)
The decoration of porous membranes with a dense layer of nanoparticles imparts useful functionality and can enhance membrane separation and anti-fouling properties. However, manufacturing of nanoparticle-coated membranes requires multiple steps and tedious processing. Here, we introduce a facile single-step method
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