A78403
4-Aminopyridine
98%
Synonym(s):
4-Pyridinamine, 4-Pyridylamine, 4AP, Fampridine
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About This Item
assay
98%
form
crystals
bp
273 °C (lit.)
mp
155-158 °C (lit.)
solubility
H2O: 50 mg/mL, clear, colorless
SMILES string
Nc1ccncc1
InChI
1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
InChI key
NUKYPUAOHBNCPY-UHFFFAOYSA-N
Gene Information
human ... KCNA1(3736), KCNA10(3744), KCNA2(3737), KCNA3(3738), KCNA4(3739), KCNA5(3741), KCNA6(3742), KCNA7(3743), KCNB1(3745), KCNB2(9312), KCNC1(3746), KCNC2(3747), KCNC3(3748), KCNC4(3749), KCND1(3750), KCND2(3751), KCND3(3752), KCNF1(3754), KCNG1(3755), KCNG2(26251), KCNG3(170850), KCNG4(93107), KCNH1(3756), KCNH2(3757), KCNH3(23416), KCNH4(23415), KCNH5(27133), KCNH6(81033), KCNH7(90134), KCNH8(131096), KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479), KCNS1(3787), KCNS2(3788), KCNS3(3790), KCNV1(27012), KCNV2(169522)
mouse ... Kcna3(16491)
rat ... Grin2a(24409)
General description
Application
- Catalyst in the regioselective acylation of N-tosylhydrazide.
- Starting material in the synthesis of 4-aminopyridine derivatives for neurological disorder studies.
- Precursor for the synthesis of enantiomerically pure 4-(pyrrolidino)pyridine (PPY) derivatives by cyclocondensation reaction.
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signalword
Danger
Hazard Classifications
Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
312.8 °F
flash_point_c
156 °C
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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