A9563
4-Aminophenylmercuric acetate
≥90% (titration)
Synonym(s):
4-(Acetoxymercurio)aniline, APMA
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About This Item
Linear Formula:
CH3CO2HgC6H4NH2
CAS Number:
Molecular Weight:
351.75
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
EC Number:
228-497-1
Beilstein/REAXYS Number:
3664749
MDL number:
Quality Level
assay
≥90% (titration)
form
powder
mp
163-165 °C (lit.)
solubility
DMSO: soluble 10 mg/mL, H2O: soluble 5 mM, glacial acetic acid: soluble 50 mg/mL
SMILES string
CC(=O)O[Hg]c1ccc(N)cc1
InChI
1S/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1
InChI key
RXSUFCOOZSGWSW-UHFFFAOYSA-M
Biochem/physiol Actions
An organomercurial activator of matrix metalloproteinases.
Disclaimer
For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.
signalword
Danger
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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A Bianchi et al.
Osteoarthritis and cartilage, 24(11), 1961-1969 (2016-10-21)
Fibroblast Growth Factor 23 (FGF23) may represent an attractive candidate that could participate to the osteoarthritic (OA)-induced phenotype switch of chondrocytes. To address this hypothesis, we investigated the expression of FGF23, its receptors (FGFRs) and co-receptor (Klotho) in human cartilage
Jan-Olof Winberg et al.
European journal of biochemistry, 270(19), 3996-4007 (2003-09-27)
In the leukemic macrophage cell-line THP-1, a fraction of the secreted matrix metalloproteinase 9 (MMP-9) is linked to the core protein of chondroitin sulfate proteoglycans (CSPG). Unlike the monomeric and homodimeric forms of MMP-9, the addition of exogenous CaCl2 to
Equine laminitis: glucose deprivation and MMP activation induce dermo-epidermal separation in vitro.
K R French et al.
Equine veterinary journal, 36(3), 261-266 (2004-05-19)
Acute laminitis is characterised by hoof lamellar dermal-epidermal separation at the basement membrane (BM) zone. Hoof lamellar explants cultured in vitro can also be made to separate at the basement membrane zone and investigating how this occurs may give insight