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Merck

P-055

Propranolol hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C16H21NO2·HCl
CAS Number:
318-98-9
Molecular Weight:
295.80
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-659-6

Product Name

Propranolol hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

InChI key

ZMRUPTIKESYGQW-UHFFFAOYSA-N

InChI

1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H

SMILES string

Cl.CC(C)NCC(O)COc1cccc2ccccc12

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

Quality Level

300

Gene Information

human ... ADRB1(153), ADRB2(154)

Related Categories

General description

A certified reference solution suitable for use as starting material in calibrators and controls for LC/MS or GC/MS testing methods in clinical and diagnostic testing, urine drug testing, forensic analysis, or clinical toxicology. Propranolol is a sympatholytic non-selective beta blocker used to treat a variety of medical conditions including hypertension, anxiety and panic. The drug is sold under numerous brand names such as Inderal®, Avlocardyl, Deralin, and Dociton.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Inderal is a registered trademark of Cranford Pharmaceuticals, LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bojko Bjelakovic et al.
Drug design, development and therapy, 7, 127-129 (2013-03-08)
We hypothesized that some characteristics of beta-blockers, including negative inotropic, peripheral vasoconstrictor, and antiangiogenic effects, might be potentially useful in treating children with epistaxis. From June 2010 to March 2012, a total of seven children with recurrent primary epistaxis resistant
Oral propranolol versus placebo for retinopathy of prematurity: a pilot, randomised, double-blind prospective study.
Imad R Makhoul et al.
Archives of disease in childhood, 98(7), 565-567 (2013-05-02)
[Propranolol first choice in infantile hemangiomas. Large randomized trials are needed to determine the dosage and duration of treatment].
Carl-Fredrik Wahlgren
Lakartidningen, 110(19-20), 938-939 (2013-06-12)
[Propanolol effective treatment for laryngo-tracheal hemangioma].
Markus Granholm et al.
Lakartidningen, 110(19-20), 947-948 (2013-06-12)
Philip M Short et al.
American journal of respiratory and critical care medicine, 187(12), 1308-1314 (2013-04-19)
Unblinded studies have shown improvements in airway hyperresponsiveness with chronic nadolol in steroid-naive patients with asthma. To assess the effects of chronic nonselective β-blockade as add-on to inhaled corticosteroids (ICS) in patients with asthma. A double-blind randomized placebo-controlled crossover trial
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