178455
Apolipoprotein A-II, Human Plasma, High-Density Lipoprotein
Native apolipoprotein A-II from human plasma. The second most abundant protein of HDL. Binds to phospholipids during lipoprotein metabolism. Displaces LCAT bound to lipoprotein.
Synonym(s):
Apo A-II
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About This Item
NACRES:
NA.77
UNSPSC Code:
12352202
Form:
liquid
Assay:
≥95% (SDS-PAGE)
assay
≥95% (SDS-PAGE)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
shipped in
wet ice
storage temp.
−20°C
Quality Level
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Toxicity: Standard Handling (A)
General description
Native apolipoprotein A-II from human plasma. Shown to bind to phospholipids during lipoprotein metabolism. Displaces lecithin-cholesterol acyltransferase bound to lipoprotein. Influences HDL functional states and contributes to arteriosclerosis.
Other Notes
Fu, L., et al. 2001. J. Histochem. Cytochem.49, 739.
Hedrick, C.C., and Lusis, A.J. 1994. Can. J. Cardiol.10, 453.
Breslow, J.L. 1993. Proc. Natl. Acad. Sci. USA 90, 8314.
Schultz, J.R., et al. 1992. J. Biol. Chem.267, 21630.
Hedrick, C.C., and Lusis, A.J. 1994. Can. J. Cardiol.10, 453.
Breslow, J.L. 1993. Proc. Natl. Acad. Sci. USA 90, 8314.
Schultz, J.R., et al. 1992. J. Biol. Chem.267, 21630.
Packaging
Please refer to vial label for lot-specific concentration.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C). Store undiluted.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Andrzej S Pitek et al.
PloS one, 7(7), e40685-e40685 (2012-07-26)
It is now well established that the surface of nanoparticles (NPs) in a biological environment is immediately modified by the adsorption of biomolecules with the formation of a protein corona and it is also accepted that the protein corona, rather
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