8.52097
Fmoc-Lys(biotin)-OH
≥95% (TLC), for peptide synthesis, Novabiochem®
Synonym(s):
Fmoc-Lys(biotin)-OH, N-α-Fmoc-N-ε-biotinyl-L-lysine
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About This Item
Product Name
Fmoc-Lys(biotin)-OH, Novabiochem®
Quality Level
product line
Novabiochem®
assay
≥85.0% (HPLC), ≥95% (TLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
biotin
storage temp.
2-30°C
SMILES string
S1[C@H]([C@H]5NC(=O)N[C@H]5C1)CCCCC(=O)NCCCC[C@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)C(=O)O
InChI
1S/C31H38N4O6S/c36-27(15-6-5-14-26-28-25(18-42-26)33-30(39)35-28)32-16-8-7-13-24(29(37)38)34-31(40)41-17-23-21-11-3-1-9-19(21)20-10-2-4-12-22(20)23/h1-4,9-12,23-26,28H,5-8,13-18H2,(H,32,36)(H,34,40)(H,37,38)(H2,33,35,39)/t24-,25-,26-,28-/m0/s1
InChI key
OFIBQNGDYNGUEZ-OBXRUURASA-N
General description
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Biotinylation Reagents for Peptide Synthesis
Application
- Supplemental Information for: Describes the reaction of amino functionalized resin with HCTU-activated Fmoc-Lys(biotin)-OH in DMF to install a biocytin molecule. Fmoc was deprotected by 20% (K Sapkota, JK Lucas, JW Faulkner, MF Lichte, YL Guo, tandf.figshare.com).
Analysis Note
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA2)): ≥ 95 %
Assay (HPLC, area%): ≥ 85.0 % (a/a)
Solubility (0,1 mmole in 1 ml NMP): clearly soluble
Water (K. F.): ≤ 3.0 %
This product can contain up to 10% DMF in order to assure an ideal solubility.
To see the solvent systems used for TLC of Novabiochem® products please click here.
Other Notes
Legal Information
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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