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About This Item
Linear Formula:
CH3SO2O(CH2)4OSO2CH3
CAS Number:
Molecular Weight:
246.30
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-250-2
Beilstein/REAXYS Number:
1791786
MDL number:
UNSPSC Code:
41116107
Quality Level
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
114-117 °C (lit.)
application(s)
forensics and toxicology
veterinary
format
neat
SMILES string
CS(=O)(=O)OCCCCOS(C)(=O)=O
InChI
1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3
InChI key
COVZYZSDYWQREU-UHFFFAOYSA-N
General description
Busulfan is a bifunctional alkylating agent, which may find application in the treatment of chronic granulocytic leukemia.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 1A - Muta. 1B - Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Blood and Marrow Stem Cell Transplantation: Principles, Practice, and Nursing Insights (1997)
Arnon Nagler et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(28), 3549-3556 (2013-08-28)
Cyclophosphamide (Cy) combined with total-body irradiation (TBI) or with busulfan (Bu) are currently the most common myeloablative regimens used in allogeneic stem-cell transplantation (alloSCT) in adults with acute myelogenous leukemia (AML). Intravenous (IV) Bu has more predictable bioavailability and a
Manabu Ozawa et al.
Biology of reproduction, 94(4), 92-92 (2016-03-18)
The F-box and leucine-rich repeat protein 10 (Fbxl10) gene encodes a protein that catalyzes demethylation of H3K4 and H3K36. In this study, we show the important roles of FBXL10 as a histone demethylase in sustainable sperm production using mice in

