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Merck

A9920

β-Alanine

BioReagent, suitable for cell culture, suitable for insect cell culture

Synonym(s):

β-Ala, 3-Aminopropionic acid

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About This Item

Linear Formula:
NH2CH2CH2COOH
CAS Number:
107-95-9
Molecular Weight:
89.09
NACRES:
NA.75
PubChem Substance ID:
24891409
eCl@ss:
39030936
UNSPSC Code:
12352209
EC Number:
203-536-5
MDL number:
MFCD00008200
Beilstein/REAXYS Number:
906793

Product Name

β-Alanine, BioReagent, suitable for cell culture, suitable for insect cell culture

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

InChI key

UCMIRNVEIXFBKS-UHFFFAOYSA-N

SMILES string

NCCC(O)=O

product line

BioReagent

assay

≥98% (TLC)

form

powder or crystals

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

color

white

mp

202 °C (dec.) (lit.)

Quality Level

300

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Biochem/physiol Actions

Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine is a component of pantothenic acid.
β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

General description

An N-blocked form of alanine.

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN5362
BCCM7651
BCCG9832
BCCG3395
BCCF7963

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Ramin Artang et al.
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The American journal of medicine, 127(4), 329-336 (2013-12-24)
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Wim Derave et al.
Sports medicine (Auckland, N.Z.), 40(3), 247-263 (2010-03-05)
Carnosine is a dipeptide with a high concentration in mammalian skeletal muscle. It is synthesized by carnosine synthase from the amino acids L-histidine and beta-alanine, of which the latter is the rate-limiting precursor, and degraded by carnosinase. Recent studies have
Robert G Hart et al.
The Canadian journal of cardiology, 29(7 Suppl), S71-S78 (2013-06-29)
Chronic kidney disease (CKD) is prevalent in elderly patients with atrial fibrillation and is an independent risk factor for stroke. Warfarin anticoagulation is efficacious for stroke prevention in atrial fibrillation patients with moderate CKD (stage III, estimated glomerular filtration rate
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