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About This Item
Linear Formula:
CsCl
CAS Number:
Molecular Weight:
168.36
NACRES:
NA.75
PubChem Substance ID:
UNSPSC Code:
12352207
EC Number:
231-600-2
MDL number:
Assay:
≥99.0%
Form:
powder
Product Name
Cesium chloride, Grade I, ≥99.0%
InChI key
AIYUHDOJVYHVIT-UHFFFAOYSA-M
InChI
1S/ClH.Cs/h1H;/q;+1/p-1
SMILES string
[Cl-].[Cs+]
type
Grade I
assay
≥99.0%
form
powder
mp
645 °C (lit.)
absorption
≤0.2 at 280 in H2O at 50%
application(s)
hematology
histology
Quality Level
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Analysis Note
Solutions may contain a slight haze.
Application
Cesium chloride has been used as a component of pipette solution, to record mechanosensitive currents in dorsal root ganglia neurons. It has been used in patch clamping to study neurons in intact myenteric ganglia.
Used for the preparation of electrically conducting glasses.Used to make solutions for the separation of RNA from DNA by density gradient centrifugation.
Biochem/physiol Actions
Oral intake of cesium chloride is known to increase the pH in cancer cells. Mild toxicity of cesium chloride might cause hypotension, gastrointestinal distress, numbness and syncope. It also leads to severe hypokalemia, hypomagnesemia, acute heart attack and polymorphic ventricular tachycardia in episodes.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Recording of mechanosensitive currents using piezoelectrically driven mechanostimulator
Jizhe H, et al.
Nature Protocols, 6(7), 979-979 (2011)
Patch clamp recording from enteric neurons in situ
Nancy O, et al.
Nature Protocols, 6(1), 15-15 (2011)
Petr Melnikov et al.
Biological trace element research, 135(1-3), 1-9 (2009-08-06)
The knowledge about cesium metabolism and toxicity is sparse. Oral intake of cesium chloride has been widely promoted on the basis of the hypothesis referred to as "high pH cancer therapy", a complimentary alternative medicine method for cancer treatment. However
Structure, dynamics, and hydration of POPC/POPS bilayers suspended in NaCl, KCl, and CsCl solutions.
Piotr Jurkiewicz et al.
Biochimica et biophysica acta, 1818(3), 609-616 (2011-12-14)
Effects of alkali metal chlorides on the properties of mixed negatively charged lipid bilayers are experimentally measured and numerically simulated. Addition of 20mol% of negatively charged phosphatidylserine to zwitterionic phosphatidylcholine strengthens adsorption of monovalent cations revealing their specificity, in the
Takafumi Yamamoto et al.
Inorganic chemistry, 50(22), 11787-11794 (2011-10-25)
The rock salt (B1) structure of binary oxides or chalcogenides transforms to the CsCl (B2) structure under high pressure, with critical pressures P(s) depending on the cation to anion size ratio (R(c)/R(a)). We investigated structural changes of A(2)MO(3) (A =
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