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Merck

I9148

Sodium iodoacetate

powder, ≥98%

Synonym(s):

Iodoacetic acid sodium salt

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About This Item

Linear Formula:
ICH2COONa
CAS Number:
305-53-3
Molecular Weight:
207.93
NACRES:
NA.77
PubChem Substance ID:
24896151
UNSPSC Code:
12352202
EC Number:
206-165-7
MDL number:
MFCD00002686
Beilstein/REAXYS Number:
4009322

Product Name

Sodium iodoacetate, ≥98%, BioUltra

InChI

1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1

InChI key

AGDSCTQQXMDDCV-UHFFFAOYSA-M

SMILES string

[Na+].[O-]C(=O)CI

biological source

synthetic (organic)

product line

BioUltra

assay

≥98%

form

powder

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp

208 °C (dec.) (lit.)

solubility

H2O: 0.5 M, clear, colorless

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.001%
Fe: ≤0.0005%
K: ≤0.02%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

−20°C

Quality Level

200

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Application

Reagent for the modification of cysteine residues in proteins.
Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

hcodes

H301,H314

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

406.4 °F

flash_point_c

208 °C

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
0000362756
0000324852
0000324853
0000362756
0000324853

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Helena Akerud et al.
American journal of physiology. Endocrinology and metabolism, 297(6), E1414-E1419 (2009-10-15)
It is generally believed that a relationship exists between muscle fatigue and intracellular accumulation of lactate. This reasoning is relevant to obstetrical issues. Myocytes in uterus work together during labor, and the contractions need to be strong and synchronized for
Mohammed Gagaoua et al.
Journal of agricultural and food chemistry, 63(30), 6799-6809 (2015-07-15)
Many studies on color biochemistry and protein biomarkers were undertaken in post-mortem beef muscles after ≥24 hours. The present study was conducted on Longissimus thoracis muscles of 21 Blond d'Aquitaine young bulls to evaluate the relationships between protein biomarkers present
Joon Shik Yoon et al.
American journal of physical medicine & rehabilitation, 94(8), 644-648 (2014-11-22)
The aim of this study was to investigate the potential of using phase-contrast radiography to detect early changes in articular cartilage in a mouse model of osteoarthritis. An iodoacetate-induced mouse model of osteoarthritis was used. Mice with iodoacetate-induced osteoarthritis were
K Nakyinsige et al.
Meat science, 98(4), 701-708 (2014-08-05)
This study assessed the effect of gas stunning which has not been conducted until now in comparison with slaughter without stunning on the welfare and meat quality of rabbits. Eighty male New Zealand White rabbits were divided into two groups
Hyunji Lee et al.
Bioscience, biotechnology, and biochemistry, 78(10), 1703-1709 (2014-10-03)
Deer bone extract has the potential to relieve the discomfort or the articular cartilaginous damage associated with osteoarthritic (OA) and may be useful as a natural supplement for OA treatment without serious side effects. We analyzed the expression of pro-inflammatory
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