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Merck

SAB5702109

Anti-Placental lactogen (CSH1) Antibody, clone 7U9T2, Rabbit Monoclonal

Synonym(s):

CSH1, CS-1, CSA, CSMT, GHB3, PL, hCS-1, hCS-A, chorionic somatomammotropin hormone 1

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
7U9T2, monoclonal
Application:
IF, IHC
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

7U9T2, monoclonal

form

liquid

species reactivity

human

concentration

0.50 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200, immunohistochemistry: 1:50 - 1:200

color

colorless

isotype

IgG

immunogen sequence

MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLE

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

General description

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Placental lactogen (CSH1) (CSH1) (P0DML2).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

IHC, IF/ICC


Storage Class

10 - Combustible liquids

wgk

WGK 1



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