Product Name
Transferrin human, Optiferrin™, recombinant, expressed in rice
biological source
human
recombinant
expressed in rice
assay
≥95% (agarose gel electrophoresis)
form
powder
composition
Protein, ≥90%
Iron content
≥300 μg/g
technique(s)
immunoprecipitation (IP): suitable
tissue culture: suitable
impurities
≤1.0 EU/mg Endotoxin
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
human ... TF(7018)
Legal Information
Optiferrin is a trademark of InVitria
rhTF manufactured in the USA by InVitria US Pat 9321828
Application
Transferrin Human has been used to perform immunoprecipitation measurements. It has also been used for the preparation of essential 8 medium.
Biochem/physiol Actions
Human transferrin was shown to promote allogeneic chimerism in mice after irradiation and transplantation of incompatible bone marrow.
Transferrin facilitates the transfer of iron to erythron and peripheral tissues. It stimulates the proliferation of human lymphocytes. Mutations in this gene are linked to atransferrinemia.
General description
Transferrin is an 80 kDa serum glycoprotein, which is expressed in hepatocytes. The gene is located on human chromosome 3q22.1.
Optiferrin™ is recombinant human transferrin that is completelyblood-free. Optiferrin’s performance is equivalent to human holo transferrin incell culture and offers significant regulatory advantages due to its safety andconsistency. Optiferrin is suitable for a broad range of cell types thatinclude stem, primary, and bioproduction cells.
Optiferrin™ is recombinant human transferrin that is completelyblood-free. Optiferrin’s performance is equivalent to human holo transferrin incell culture and offers significant regulatory advantages due to its safety andconsistency. Optiferrin is suitable for a broad range of cell types thatinclude stem, primary, and bioproduction cells.
Other Notes
1). Patent Rights
U.S. Patent No. 9,321,828
2). Registered Trademark Rights
U.S. Reg. 3,880,881
International Reg. 1,466,509
U.S. Patent No. 9,321,828
2). Registered Trademark Rights
U.S. Reg. 3,880,881
International Reg. 1,466,509
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Effect of transferrin, lactoferrin and chelated iron on human T-lymphocytes
Djeha A and Brock JH
British Journal of Haematology, 80(2), 235-241 (1992)
TFRC (transferrin receptor (p90, CD71))
Dorak MT
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2009)
Derivation of highly purified cardiomyocytes from human induced pluripotent stem cells using small molecule-modulated differentiation and subsequent glucose starvation
Sharma A, et al.
Journal of Visualized Experiments, (97) (2015)
Chemically defined culture and cardiomyocyte differentiation of human pluripotent stem cells
Burridge PW, et al.
Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et al.], 87(1), 21-23 (2015)
Increasing serum transferrin to reduce tissue iron overload due to ineffective erythropoiesis
Tolosano E
The Hematology Journal : The Official Journal of the European Haematology Association / EHA (2015)
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