190047
(−)-p-Bromolevamisole oxalate
99%
Synonym(s):
(−)-4-Bromotetramisole oxalate, 6-Bromolevamisole oxalate, S(−)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate
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About This Item
Empirical Formula (Hill Notation):
C11H11BrN2S · C2H2O4
CAS Number:
Molecular Weight:
373.22
UNSPSC Code:
12352200
NACRES:
NA.06
PubChem Substance ID:
EC Number:
263-487-0
Beilstein/REAXYS Number:
4944883
MDL number:
Assay:
99%
Form:
powder
Quality Level
assay
99%
form
powder
optical activity
[α]25/D −104°, c = 0.5 in H2O
mp
192 °C (dec.) (lit.)
functional group
bromo, carboxylic acid, thioether
SMILES string
OC(=O)C(O)=O.Brc1ccc(cc1)[C@H]2CN3CCSC3=N2
InChI
1S/C11H11BrN2S.C2H2O4/c12-9-3-1-8(2-4-9)10-7-14-5-6-15-11(14)13-10;3-1(4)2(5)6/h1-4,10H,5-7H2;(H,3,4)(H,5,6)/t10-;/m1./s1
InChI key
ZULBIBHDIQCNIS-HNCPQSOCSA-N
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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D E Amacher et al.
Enzyme, 42(1), 1-7 (1989-01-01)
Alkaline phosphatase (AP) from the sera of both male and female beagle dogs was partially purified and then analyzed for the presence of AP isoenzymes having intestinal or osseous characteristics as detected by bromotetramisole inhibition or wheat germ lectin agarose
Measurement of alkaline phosphatase of intestinal origin in plasma by p-bromotetramisole inhibition.
T Kuwana et al.
Journal of clinical pathology, 44(3), 236-237 (1991-03-01)
L-p-bromotetramisole was used to inhibit non-intestinal alkaline phosphatase (of liver or bone origin) (EC 3.1.3.1; ALP) in plasma, and intestinal ALP was measured from the uninhibited activity. The method of determination is convenient and correlated well with measurement by immunocapture
F Becq et al.
The Journal of biological chemistry, 271(27), 16171-16179 (1996-07-05)
Patch-clamp, iodide efflux, and biochemical techniques were used to evaluate the ability of phenylimidazothiazoles to open normal and mutated cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels and to investigate the mechanism of activation. As reported previously for bromotetramisole, levamisole