202487
Poly(ethylene glycol) methyl ether
average MN 550, methoxy, hydroxyl
Synonym(s):
Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG
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About This Item
Linear Formula:
CH3(OCH2CH2)nOH
CAS Number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
MDL number:
Product Name
Poly(ethylene glycol) methyl ether, average Mn 550
vapor density
>1 (vs air)
Quality Level
vapor pressure
0.05 mmHg ( 20 °C)
form
semisolid
mol wt
average Mn 550
refractive index
n20/D 1.455
viscosity
7.5 cSt(210 °F)(lit.)
transition temp
Tm 20 °C
density
1.089 g/mL at 25 °C
Ω-end
hydroxyl
α-end
methoxy
SMILES string
O(CCO)C
InChI
1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
InChI key
XNWFRZJHXBZDAG-UHFFFAOYSA-N
Application
Poly(ethylene glycol) methyl ether can be used as a pore-forming agent to prepare polysulfone membranes with enhanced hydrophilicity.
Poly(ethylene glycol) methyl ether-grafted polyamidoamine (PAMAM) dendrimers can be used as drug carrier systems for anticancer drugs.
Poly(ethylene glycol) methyl ether-grafted polyamidoamine (PAMAM) dendrimers can be used as drug carrier systems for anticancer drugs.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
359.6 °F - closed cup
flash_point_c
182 °C - closed cup
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Jiani Zheng et al.
Langmuir : the ACS journal of surfaces and colloids, 28(37), 13261-13273 (2012-08-28)
Alginate/chitosan/alginate (ACA) hydrogel microcapsules were modified with methoxy poly(ethylene glycol) (MPEG) to improve protein repellency and biocompatibility. Increased MPEG surface graft density (n(S)) on hydrogel microcapsules was achieved by controlling the grafting parameters including the buffer layer substrate, membrane thickness
Curcumin loaded polymeric micelles inhibit breast tumor growth and spontaneous pulmonary metastasis.
Lei Liu et al.
International journal of pharmaceutics, 443(1-2), 175-182 (2013-01-05)
This work aims to develop curcumin (Cur) loaded biodegradable self-assembled polymeric micelles (Cur-M) to overcome poor water solubility of Cur and to meet the requirement of intravenous administration. Cur-M were prepared by solid dispersion method, which was simple and easy
Yiyi Yu et al.
Journal of pharmaceutical sciences, 102(3), 1054-1062 (2013-01-03)
To promote the application of methoxy poly(ethylene glycol)-cholesterol (mPEG-Chol), mPEG-Chol was used to prepare core-shell micelles encapsulating poorly water-soluble docetaxel (DTX-PM) by modified cosolvent evaporation method. Approaches to enhance DTX entrapment efficiency (EE) and minimize particle size were investigated in