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Merck

320617

Ethyl 4-hydroxy-3-methoxycinnamate

98%

Synonym(s):

Ethyl ferulate

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About This Item

Linear Formula:
HOC6H3(OCH3)CH=CHCO2C2H5
CAS Number:
Molecular Weight:
222.24
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
223-745-5
MDL number:
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Product Name

Ethyl 4-hydroxy-3-methoxycinnamate, 98%

InChI key

ATJVZXXHKSYELS-FNORWQNLSA-N

InChI

1S/C12H14O4/c1-3-16-12(14)7-5-9-4-6-10(13)11(8-9)15-2/h4-8,13H,3H2,1-2H3/b7-5+

SMILES string

CCOC(=O)\C=C\c1ccc(O)c(OC)c1

assay

98%

form

solid

bp

164-166 °C/0.5 mmHg (lit.)

mp

63-65 °C (lit.)

functional group

ester

Quality Level

Related Categories

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Jasmine Bhathena et al.
PloS one, 8(3), e58394-e58394 (2013-04-05)
The beneficial effect of a microencapsulated feruloyl esterase producing Lactobacillus fermentum ATCC 11976 formulation for use in non-alcoholic fatty liver disease (NAFLD) was investigated. For which Bio F1B Golden Syrian hamsters were fed a methionine deficient/choline devoid diet to induce
F Di Domenico et al.
Free radical research, 43(4), 365-375 (2009-03-11)
UV solar radiation is the major environmental risk factor for malignant melanoma. A great effort is currently posed on the search of new compounds able to prevent or reduce UV-mediated cell damage. Ferulic acid is a natural compound recently included
Ashok Kumar et al.
Bioresource technology, 102(3), 2162-2167 (2010-11-03)
In the present work we have evaluated synthesis of ethyl ferulate by the esterification reaction of ferulic acid and ethanol catalyzed by a commercial lipase (Steapsin) immobilized onto celite-545 in a short period of 6h in DMSO. The immobilized lipase
Vittorio Calabrese et al.
Clinics in dermatology, 26(4), 358-363 (2008-08-12)
Skin is one of the main targets for reactive oxygen species; thus, reactive oxygen species-induced damage and protein and lipid modifications occur, and skin can undergo a wide array of diseases, from photosensitivity to cancer. In this study, human dermal
Kin Kwan Lai et al.
Applied and environmental microbiology, 75(15), 5018-5024 (2009-06-09)
Cinnamic acids (i.e., ferulic and caffeic acids) that are esterified to the vegetable cell walls should be enzymatically released to be absorbed in a mammal's intestines. A low dosage of ferulic acid in rodent diets stimulates insulin production and alleviates

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