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Merck

382310

Didecyldimethylammonium bromide

98%

Synonym(s):

DDAB

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About This Item

Linear Formula:
[CH3(CH2)9]2N(CH3)2Br
CAS Number:
Molecular Weight:
406.53
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
EC Number:
219-234-1
Beilstein/REAXYS Number:
6492993
MDL number:
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Product Name

Didecyldimethylammonium bromide, 98%

InChI key

UMGXUWVIJIQANV-UHFFFAOYSA-M

InChI

1S/C22H48N.BrH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1

SMILES string

[Br-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC

assay

98%

mp

149-151 °C (lit.)

Quality Level

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Application

Didecyldimethylammonium bromide (DDAB) is commonly used as a surfactant and a phase transfer catalyst. It is also used in the preparation of hydrophobic ammonium-based ionic liquid.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Chiara Botto et al.
International journal of pharmaceutics, 516(1-2), 334-341 (2016-11-28)
Solid lipid nanoparticles (SLNs) may be considered as a new approach for therapeutics for many diseases. In addition to drug delivery, their use as non-viral vectors for gene delivery can be obtained by including cationic lipids, which provide a positive
Christopher J Ioannou et al.
Antimicrobial agents and chemotherapy, 51(1), 296-306 (2006-10-25)
Mode-of-action studies concluded that alkyldimethylbenzylammonium chloride (ADBAC) (a blend of C(12), C(14) and C(16) alkyl homologues) and didecyldimethylammonium chloride (DDAC) are both membrane-active agents, possessing subtly different modes of action reflecting early cell interactions against Staphylococcus aureus. ADBAC and DDAC
Xiangwen Liu et al.
Scientific reports, 3, 1404-1404 (2013-03-09)
Nanomaterials with particular nanostructures which usually possess special properties always attract considerable attention. A novel bimetallic Pt/Cu hexapod nanostructure was prepared by a facile one-pot strategy. The formation mechanism was investigated by the time sequential evolution experiments and the hexapod
Regis Marty et al.
Nucleic acids research, 37(15), 5197-5207 (2009-06-30)
Despite considerable interest and investigations on cationic lipid-DNA complexes, reports on lipid-RNA interaction are very limited. In contrast to lipid-DNA complexes where lipid binding induces partial B to A and B to C conformational changes, lipid-tRNA complexation preserves tRNA folded
C Carbone et al.
Colloids and surfaces. B, Biointerfaces, 167, 337-344 (2018-04-24)
In this work, we aimed at developing an improved topical SLN formulation combining itraconazole delivery with a coating layer of didodecyldimethylammonium bromide, thus repurposing the drug effectiveness by synergistic skin anticancer effectiveness. In order to obtain a stable SLN formulation

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