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852473

5-Bromouracil

Name: 5-Bromouracil
Brand: ALDRICH

98%

Synonym(s):

5-Bromo-2,4-dihydroxypyrimidine

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About This Item

Empirical Formula (Hill Notation):

C₄H₃BrN₂O₂

CAS Number:

51-20-7

Molecular Weight:

190.98

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24888322

EC Number:

200-084-0

Beilstein/REAXYS Number:

127176

MDL number:

MFCD00006017

Assay:

98%

Form:

crystals

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Properties

Quality Level

100

assay

98%

form

crystals

mp

>300 °C (lit.)

functional group

bromo

SMILES string

BrC1=CNC(=O)NC1=O

InChI

1S/C4H3BrN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)

InChI key

LQLQRFGHAALLLE-UHFFFAOYSA-N

Description

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Photoreactivities of 5-bromouracil-containing RNAs.

Hironobu Morinaga et al.

Bioorganic & medicinal chemistry, 21(2), 466-469 (2012-12-26)

5-Bromouracil ((Br)U) was incorporated into three types of synthetic RNA and the products of the photoirradiated (Br)U-containing RNAs were investigated using HPLC and MS analysis. The photoirradiation of r(GCA(Br)UGC)(2) and r(CGAA(Br)UUGC)/r(GCAAUUCG) in A-form RNA produced the corresponding 2'-keto adenosine ((keto)A)

The distance between donor and acceptor affects the proportion of C1' and C2' oxidation products of DNA in a BrU-containing excess electron transfer system.

Ryu Tashiro et al.

Journal of the American Chemical Society, 132(41), 14361-14363 (2010-09-30)

We have investigated the products of (Br)U in excess electron transfer and have demonstrated that in DNA the proportion of products changes with the distance between the donor and acceptor. On the basis of a labeling experiment using H(2)(18)O, we

The lesions produced by ultraviolet light in DNA containing 5-bromouracil.

F Hutchinson

Quarterly reviews of biophysics, 6(2), 201-246 (1973-05-01)

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