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Merck

857653

trans-4-(Aminomethyl)cyclohexanecarboxylic acid

97%

Synonym(s):

AMCA, AMCHA, HAKU, TAMCHA, Tranexamic acid

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About This Item

Linear Formula:
H2NCH2C6H10CO2H
CAS Number:
1197-18-8
Molecular Weight:
157.21
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24888448
EC Number:
214-818-2
Beilstein/REAXYS Number:
2207452
MDL number:
MFCD00001466

Key Documents

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Product Name

trans-4-(Aminomethyl)cyclohexanecarboxylic acid, 97%

InChI key

GYDJEQRTZSCIOI-LJGSYFOKSA-N

InChI

1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-

SMILES string

NC[C@H]1CC[C@@H](CC1)C(O)=O

assay

97%

form

powder

mp

>300 °C (lit.)

functional group

amine
carboxylic acid

Quality Level

200

Gene Information

human ... PLG(5340)

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Related Categories

Application

Used as a lysine analogue to characterize binding sites in plasminogen.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB4516
SDBB2341
STBL3493
STBJ7761
STBK9826

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Thomas Forro et al.
Cerebral cortex (New York, N.Y. : 1991), 25(5), 1228-1240 (2013-11-28)
Travelling theta oscillations and sharp wave-associated ripples (SWRs) provide temporal structures to neural activity in the CA1 hippocampus. The contribution of rhythm-generating GABAergic interneurons to network timing across the septotemporal CA1 axis remains unknown. We recorded the spike-timing of identified
V Sharma et al.
Anaesthesia, 69(2), 124-130 (2014-03-04)
Because of a lack of contemporary data regarding seizures after cardiac surgery, we undertook a retrospective analysis of prospectively collected data from 11 529 patients in whom cardiopulmonary bypass was used from January 2004 to December 2010. A convulsive seizure
Sattar Alshryda et al.
The Journal of bone and joint surgery. American volume, 95(21), 1961-1968 (2013-11-08)
Approximately one-third of patients undergoing total knee replacement require one to three units of blood postoperatively. Tranexamic acid (TXA) is a synthetic antifibrinolytic agent that has been successfully used intravenously to stop bleeding after total knee replacement. A topical application
Sattar Alshryda et al.
The Journal of bone and joint surgery. American volume, 95(21), 1969-1974 (2013-11-08)
Approximately one-third of patients undergoing total hip replacement surgery require one to three units of blood postoperatively. Tranexamic acid is a synthetic antifibrinolytic agent that has been successfully used intravenously to control bleeding after total hip replacement. A topical application
Joseph G Martin et al.
The Journal of arthroplasty, 29(5), 889-894 (2013-11-19)
Major blood loss is a known potential complication in total hip and total knee arthroplasty. We conducted a prospective, stratified, randomized, double-blind, placebo-controlled trial that evaluated 100 patients undergoing total knee or total hip arthroplasty to evaluate the effect on
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