T32603
2-Thiophenecarboxylic acid
ReagentPlus®, 99%
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About This Item
Empirical Formula (Hill Notation):
C5H4O2S
CAS Number:
Molecular Weight:
128.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-423-4
Beilstein/REAXYS Number:
110150
MDL number:
Assay:
99%
Product Name
2-Thiophenecarboxylic acid, ReagentPlus®, 99%
InChI key
QERYCTSHXKAMIS-UHFFFAOYSA-N
InChI
1S/C5H4O2S/c6-5(7)4-2-1-3-8-4/h1-3H,(H,6,7)
SMILES string
OC(=O)c1cccs1
product line
ReagentPlus®
assay
99%
bp
260 °C (lit.)
mp
125-127 °C (lit.)
Quality Level
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Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Mrinal K Bera et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(42), 11838-11843 (2011-09-08)
Herein, we describe our attempts to systematically prepare a series of oligo(2-thienyl)-substituted pyridine derivatives. The crucial starting material, a β-alkoxy-β-ketoenamide, is easily available on a large scale by the reaction of lithiated methoxyallene with thiophene-2-carbonitrile and thiophene-2-carboxylic acid. This three-component
D Panagoulis et al.
Journal of inorganic biochemistry, 101(4), 623-634 (2007-02-06)
Copper complexes with thiophen-2-yl saturated and alpha,beta-unsaturated carboxylic acids as ligands were prepared, characterized and pharmacochemically studied. The available evidence supports a dimeric structure for the complexes of the general formula [Cu2(L)4(MeOH)2] where L are the anions of thiophene 2-carboxylic
[Double blind study of the mucoregulating action of sodium thiophene carboxylate (author's transl)].
J C Cheminat et al.
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 57(5-6), 307-310 (1981-02-08)
A double blind study of thiophene carboxylate in 32 chronic bronchitis patients, show an improvement of clinical and respiratory condition in the treated group. However, there is no increase in volume of expectoration and no fluidizing. The product acts as
Matthew F McCown et al.
Antimicrobial agents and chemotherapy, 53(5), 2129-2132 (2009-03-11)
In vitro, telaprevir selects subtype-specific resistance pathways for hepatitis C virus GT-1a and GT-1b, as described to have occurred in patients. In GT-1a, the HCV-796 resistance mutation C316Y has low replication capacity (7%) that can be compensated for by the
Laval Chan et al.
Bioorganic & medicinal chemistry letters, 14(3), 793-796 (2004-01-27)
The discovery of a novel class of HCV NS5B polymerase inhibitors, 3-arylsulfonylamino-5-phenyl-thiophene-2-carboxylic acids is described. SAR studies have yielded several potent inhibitors of HCV polymerase as well as of HCV subgenomic RNA replication in Huh-7 cells.
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