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Merck

810143P

Avanti

14:0 NBD PE

Avanti Research - A Croda Brand

Synonym(s):

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C39H70N5O11P
CAS Number:
Molecular Weight:
815.97
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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Product Name

14:0 NBD PE, Avanti Research - A Croda Brand 810143P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810143P-1mg), pkg of 5 × 1 mg (810143P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810143P

shipped in

dry ice

storage temp.

−20°C

General description

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescently labeled lipid localized at the membrane interface. Phosphoethanolamine is the second most abundant, metabolically related aminophospholipid. It is mostly enriched in brain.

Application

14:0 NBD PE may be used in the lipid mixing assay for the preparation of phospholipid vesicles and to study its non-equilibrium and equilibrium variations in thermodynamic state of the lipid-water-interface

Biochem/physiol Actions

Phosphoethanolamine of cardiac myocytes is known to prevent cellular damage after ischemia. N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) contributes to the Red edge excitation shift (REES) effect monitoring because of its unique motional and dielectric properties.

Packaging

5 mL Amber Glass Screw Cap Vial (810143P-1mg)
5 mL Amber Glass Screw Cap Vial (810143P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids



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Application of NBD-labeled lipids in membrane and cell biology
Fluorescent methods to study biological membranes, 37-50 (2012)
In vitro Membrane Interaction and Liposome Fusion Assays Using Recombinant Hepatitis C Virus Envelope Protein E2
Shrivastava S and Schneider MF
Bio-protocol, 8(23), 543-554 (2018)
Shamit Shrivastava et al.
PloS one, 8(7), e67524-e67524 (2013-07-19)
Fluorescent dyes are vital for studying static and dynamic patterns and pattern formation in cell biology. Emission properties of the dyes incorporated in a biological interface are known to be sensitive to their local environment. We report that the fluorescence