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About This Item
Empirical Formula (Hill Notation):
C34H69NO4
CAS Number:
Molecular Weight:
555.92
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
N-16:0 Phytosphingosine, Avanti Research™ - A Croda Brand 860617P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860617P-10mg), pkg of 1 × 5 mg (860617P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860617P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO
InChI key
IVBULNXGVIHEKN-MVIDNBQJSA-N
General description
Phytosphingosine is a biologically significant saturated long-chain sphingoid base, found in membranes of yeasts, fungi, plants and mammalian epidermis, including the stratum corneum.
Application
N-16:0 Phytosphingosine has been used as a lipid standard in electrospray ionization (ESI)-mass spectrometry (MS)-based lipidomic analysis.
Biochem/physiol Actions
Phytosphingosine plays a vital role in the defense mechanism of the skin by exhibiting anti-microbial and anti-inflammatory properties. It elicits keratinocyte differentiation and is therefore, used as an active ingredient in the cosmetic formulations. PHS helps in maintaining the structural integrity of the membranes. It also regulates cellular growth and mediates the heat stress response of yeast.
Packaging
5 mL Amber Glass Screw Cap Vial (860617P-10mg)
5 mL Amber Glass Screw Cap Vial (860617P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
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Delineating the rules for structural adaptation of membrane-associated proteins to evolutionary changes in membrane lipidome
Makarova M, et al.
Current Biology (2020)
Antimicrobial Activity of Phytosphingosine Nanoemulsions against Bacteria and Yeasts
Bascpinar P, et al.
CBE Life Sciences Education, 14(2), 223-228 (2018)
Polar emollients in cosmetic formulations enhance the penetration and biological effects of Phytosphingosine on skin
Schiemann Y, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 331(1-2), 103-107 (2008)