1.07098
8-Hydroxyquinoline
GR for analysis Reag. Ph Eur
Synonym(s):
8-Hydroxyquinoline, Oxine, 8-Quinolinol
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About This Item
agency
reag. Ph. Eur.
Quality Level
form
solid
potency
1200 mg/kg LD50, oral (Rat)
bp
267 °C/1013 hPa
mp
72.5-74.0 °C
density
1.034 g/cm3 at 20 °C
storage temp.
15-25°C
SMILES string
n1c2c(ccc1)cccc2O
InChI
1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H
InChI key
MCJGNVYPOGVAJF-UHFFFAOYSA-N
Application
- Pseudo-water-soluble Fe(2)O(3) as Nanozyme catalyzed chemiluminescent reaction for detection of brilliant blue in gelatin and beverages.: This innovative study utilizes 8-Hydroxyquinoline for enhancing chemiluminescent reactions in the detection of food colorants, presenting a new avenue in food safety and quality assurance techniques (Jabbar HS, 2024).
- Enhanced selectivity towards melanoma cells with zinc(II)-Schiff bases containing imidazole derivatives.: Incorporating 8-Hydroxyquinoline in the development of zinc(II)-Schiff base complexes, this research demonstrates potential therapeutic applications in targeting melanoma cells, highlighting its role in medicinal chemistry (Côrte-Real et al., 2024).
- Synthesis, crystal structure and anti-cancer activity of the complex chlorido-(η(2)-ethyl-ene)(quinolin-8-olato-κ(2)N,O)platinum(II) by experimental and theoretical methods.: This paper details the synthesis and anti-cancer properties of a novel platinum(II) complex using 8-Hydroxyquinoline, offering insights into its structural characteristics and therapeutic potential (Chi NTT et al., 2024).
- Anticancer activity of 8-hydroxyquinoline-triphenylphosphine rhodium(III) complexes targeting mitophagy pathways.: Exploring the use of 8-Hydroxyquinoline in rhodium(III) complexes, this study provides a new perspective on targeting cancer cell metabolism, specifically through mitophagy pathways (Huang XQ et al., 2024).
- Mitochondria-localizing triphenylphosphine-8-hydroxyquinoline Ru complexes induce ferroptosis and their antitumor evaluation.: This research examines the effectiveness of 8-Hydroxyquinoline complexes in inducing ferroptosis in cancer cells, a novel approach in cancer therapy focusing on oxidative cell death mechanisms (Meng T et al., 2024).
Analysis Note
Identity (IR-spectrum): passes test
Matter insoluble in ethanol: ≤ 0.05 %
Melting point: 73 - 75 °C
Chloride (Cl): ≤ 0.001 %
Sulfate (SO₄): ≤ 0.01 %
Sulfated ash: ≤ 0.05 %
Suitability as reagent (for Mg-test): passes test
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Danger
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1
Storage Class
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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