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Merck

8.52207

Fmoc-Trp-OH

Novabiochem®

Synonym(s):

Fmoc-Trp-OH, N-α-Fmoc-L-tryptophan

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About This Item

Empirical Formula (Hill Notation):
C26H22N2O4
CAS Number:
Molecular Weight:
426.46
UNSPSC Code:
12352209
EC Index Number:
252-706-5
NACRES:
NA.22
MDL number:
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Quality Level

product line

Novabiochem®

assay

≥96.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-30°C

SMILES string

[nH]1c2c(c(c1)C[C@H](NC(=O)OCC3c4c(cccc4)c5c3cccc5)C(=O)[O-])cccc2

InChI

1S/C26H22N2O4/c29-25(30)24(13-16-14-27-23-12-6-5-7-17(16)23)28-26(31)32-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,14,22,24,27H,13,15H2,(H,28,31)(H,29,30)/p-1/t24-/m0/s1

InChI key

MGHMWKZOLAAOTD-DEOSSOPVSA-M

General description

Building block for introduction of typtophan by Fmoc SPPS. Superceded by Fmoc-Trp(Boc)-OH.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011C)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 96.0 %
Water (K. F.): ≤ 1.0 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1035

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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