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8.53018

Boc-Lys(2-Cl-Z)-OH

Name: Boc-Lys(2-Cl-Z)-OH
Brand: MM

(cryst) Novabiochem^®

Synonym(s):

Boc-Lys(2-Cl-Z)-OH, N-α-t.-Boc-N-ε-2-chloro-CBZ-L-lysine

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About This Item

Empirical Formula (Hill Notation):

C₁₉H₂₇ClN₂O₆

CAS Number:

54613-99-9

Molecular Weight:

414.88

MDL number:

MFCD00356585

UNSPSC Code:

12352209

NACRES:

NA.22

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Properties

Quality Segment

200

product line

Novabiochem^®

assay

≥95.0% (acidimetric), ≥98% (TLC), ≥99.0% (HPLC)

form

powder

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem^®

mp

70-73 °C

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

SMILES string

Clc1c(cccc1)COC(=O)NCCCCC(NC(=O)OC(C)(C)C)C(=O)O

InChI

1S/C19H27ClN2O6/c1-19(2,3)28-18(26)22-15(16(23)24)10-6-7-11-21-17(25)27-12-13-8-4-5-9-14(13)20/h4-5,8-9,15H,6-7,10-12H2,1-3H3,(H,21,25)(H,22,26)(H,23,24)

InChI key

ATUMDPHEFWGCJF-UHFFFAOYSA-N

Description

General description

Standard building block for introduction of lysine amino-acid residues by Boc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Literature references

^[1] K. Noda, et al. (1969) Bull. Chem. Soc. Jpn., 43, 1883.
^[2]B. W. Erickson, et al. (1973) J. Am. Chem. Soc., 95, 3757.

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): -12.0 - -10.0 °
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Solubility (1mmoll in 2ml DCM): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Enantiomeric purity: ≥ 99.5 % (a/a)

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-0068

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c