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Merck

MAB1912

Anti-Collagen Type I (COL1A1) Antibody

CHEMICON®, rat monoclonal, M-58

Synonym(s):

Anti-Procollagen Antibody, Clone M-58 Anti-Procollagen, Type I Procollagen Detection

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
M-58, monoclonal
Species reactivity:
human
Application:
IHC
Citations:
45
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Product Name

Anti-Procollagen Type I Antibody, NT, clone M-58, culture supernatant, clone M-58, Chemicon®

biological source

rat

Quality Level

antibody form

culture supernatant

clone

M-58, monoclonal

species reactivity

human

should not react with

rat, hamster, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable (paraffin)

isotype

IgG2α

NCBI accession no.

UniProt accession no.

target post-translational modification

unmodified

Gene Information

human ... COL1A1(1277)

Application

Detect Procollagen Type I using this Anti-Procollagen Type I Antibody, N-terminus, clone M-58 validated for use in IH(P).
Immunohistochemistry: 1:10,000-1:50,000 (fresh frozen tissue sections.)

Suitable for formaldehyde/formalin fixed paraffin sections, suggested starting dilution 1:100-1:1000, after treatment with 1% trypsin, 20 minutes at room temperature. Does not stain mature collagen fibers in tissue. Localized intracellularly in cells producing pro-collagen I. Not recommended for Western Blots Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Recognizes Human pro-collagen I. MAB1912 labels the amino-terminal pro-peptide.

Analysis Note

Control
Skin tissue

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

10 - Combustible liquids

wgk

WGK 2



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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John P McCook et al.
Clinical, cosmetic and investigational dermatology, 9, 167-174 (2016-08-16)
To examine the effect of sodium copper chlorophyllin complex on the expression of biomarkers of photoaged dermal extracellular matrix indicative of skin repair. Following a previously published 12-day clinical assessment model, skin biopsy samples from the forearms of four healthy
Are fibrocytes present in pediatric burn wounds?
Andrew J A Holland,Sarah L S Tarran,Heather J Medbury,Ann K Guiffre
Journal of Burn Care & Research : Official Publication of the American Burn Association null
Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair.
Virag, JI; Murry, CE
The American Journal of Pathology null



Global Trade Item Number

SKUGTIN
MAB191204053252465383