00893
Dextran
analytical standard, 150,000
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About This Item
Linear Formula:
[C6H10O5]n
CAS Number:
NACRES:
NA.24
UNSPSC Code:
12352201
EC Number:
232-677-5
MDL number:
Product Name
Dextran, analytical standard, 150,000
InChI key
FZWBNHMXJMCXLU-UHFFFAOYSA-N
InChI
1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
grade
analytical standard
form
crystalline
analyte chemical class(es)
oligosaccharides
technique(s)
gel permeation chromatography (GPC): suitable
Mw/Mn
~1.47
application(s)
food and beverages
Quality Level
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Application
- Wound healing hydrogels: Collagen-polyurethane-dextran hydrogels were found to enhance wound healing by reducing inflammation and promoting collagen fibrillogenesis, highlighting dextran′s utility in creating advanced biomaterials for medical applications (Aguayo-Morales et al., 2024).
- Drug delivery systems: A study on novel dextran bioconjugates for targeted therapy examined their role in enhancing the cellular uptake of antisense oligonucleotides, demonstrating dextran′s critical function in developing more efficient drug delivery systems (Kohashi et al., 2024).
General description
Dextran (mol. wt. 150,000) belongs to the family of neutral polysaccharides, which are recognized as contaminants in sugar processing and other food production industries. These are composed of chains of D-glucose units connected by alpha-(1-6) linkages of varying lengths. They are found as bacterial extracellular polysaccharides and reportedly synthesized from sucrose by beneficial lactic acid bacteria, such as Leuconostoc mesenteroides and Lactobacillus brevis. They are incorporated in bakery products to improve the crumb texture, softness, and loaf volume, as stabilizers and additives in confectionery, flavor extract, icing compositions, beverages including soft drinks, milk, etc.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
ppe
Eyeshields, Gloves, type N95 (US)
flash_point_f
Not applicable
flash_point_c
Not applicable
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Functional polymers based on dextran
Polysaccharide-based Fibers and Composites: Chemical and Engineering Fundamentals and Industrial Applications, 199-291 (2006)
Dextran?the polysaccharide with versatile uses
Bhavani LA and Nisha J
International Journal of Pharmacy and Biological Sciences, 1(4), 569-573 (2010)
Dmitri Simberg et al.
Biomaterials, 30(23-24), 3926-3933 (2009-04-28)
In order to understand the role of plasma proteins in the rapid liver clearance of dextran-coated superparamagnetic iron oxide (SPIO) in vivo, we analyzed the full repertoire of SPIO-binding blood proteins using novel two-dimensional differential mass spectrometry approach. The identified
Lamiaa M A Ali et al.
Journal of biomedical nanotechnology, 9(7), 1272-1285 (2013-08-06)
Superparamagnetic iron oxide nanoparticles (SPIONs) are inorganic nanomaterials gaining strong clinical interest due to their increasing number of biological and medical applications. The stabilization of SPIONs in a biocompatible stable suspension (bioferrofluid) is generally achieved by an adequate polymeric coating.
Elizabeth M Bradshaw et al.
Nature neuroscience, 16(7), 848-850 (2013-05-28)
In our functional dissection of the CD33 Alzheimer's disease susceptibility locus, we found that the rs3865444(C) risk allele was associated with greater cell surface expression of CD33 in the monocytes (t50 = 10.06, P(joint) = 1.3 × 10(-13)) of young
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