05164
(Aminomethyl)phosphonic acid
PESTANAL®, analytical standard
Synonym(s):
AMPA
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About This Item
Linear Formula:
NH2CH2P(O)(OH)2
CAS Number:
Molecular Weight:
111.04
UNSPSC Code:
77101502
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1701219
Product Name
(Aminomethyl)phosphonic acid, PESTANAL®, analytical standard
InChI
1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)
InChI key
MGRVRXRGTBOSHW-UHFFFAOYSA-N
SMILES string
NCP(O)(O)=O
grade
analytical standard
product line
PESTANAL®
assay
≥98.0% (TLC)
shelf life
limited shelf life, expiry date on the label
impurities
≤3.0% water (calc. from elemental analysis)
application(s)
agriculture
environmental
format
neat
Quality Level
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Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Seonil Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(10), 3122-3127 (2015-02-26)
Gene knockout (KO) does not always result in phenotypic changes, possibly due to mechanisms of functional compensation. We have studied mice lacking cGMP-dependent kinase II (cGKII), which phosphorylates GluA1, a subunit of AMPA receptors (AMPARs), and promotes hippocampal long-term potentiation
Philip Jean-Richard Dit Bressel et al.
PloS one, 9(11), e111699-e111699 (2014-11-05)
The lateral habenula (LHb) is a small epithalamic structure that projects via the fasciculus retroflexus to the midbrain. The LHb is known to modulate midbrain dopamine (DA) neurons, including inhibition of ventral tegmental area (VTA) neurons via glutamatergic excitation of
Mary L Huff et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(4), 861-873 (2014-09-27)
Recent findings suggest that the mesolimbic dopamine neurons, known to promote cocaine-seeking behavior, are strongly inhibited by a newly characterized region of the midbrain known as the rostromedial tegmental nucleus (RMTg). The RMTg appears to be involved in generating reward-prediction
W Zhou et al.
European psychiatry : the journal of the Association of European Psychiatrists, 29(7), 419-423 (2013-12-11)
Ketamine exerts fast acting, robust, and lasting antidepressant effects in a sub-anesthetic dose, however, the underlying mechanisms are still not fully elucidated. Recent studies have suggested that ketamine's antidepressant effects are probably attributed to the activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)
Martin Puskarjov et al.
Neuropharmacology, 88, 103-109 (2014-09-18)
A robust increase in the functional expression of the neuronal K-Cl cotransporter KCC2 during CNS development is necessary for the emergence of hyperpolarizing ionotropic GABAergic transmission. BDNF-TrkB signaling has been implicated in the developmental up-regulation of KCC2 and, in mature
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