29992
DL-α-Tocopherol acetate
tested according to Ph. Eur.
Synonym(s):
α-Tocopherylis acetas, Vitamin E acetate, all-rac-α-Tocopheryl acetate
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About This Item
Empirical Formula (Hill Notation):
C31H52O3
CAS Number:
Molecular Weight:
472.74
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
231-710-0
Beilstein/REAXYS Number:
97512
MDL number:
biological source
synthetic
Quality Level
agency
tested according to Ph. Eur.
assay
96.5-102.0%
form
liquid
density
0.96 g/mL at 20 °C (lit.)
application(s)
cell analysis
research use (small molecule)
storage temp.
2-8°C
SMILES string
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1
InChI
1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
InChI key
ZAKOWWREFLAJOT-CEFNRUSXSA-N
General description
α-Tocopherol is a form of vitamin E. Vitamin E can be obtained through dietary sources. RRR‐α‐tocopherol is a natural form of α-Tocopherol.
Application
DL-alpha-Tocopherol acetate was used as a vitamin E supplement for studying whether the addition of an antioxidant or vitamin E in the diet of rats with dextran sulfate sodium (DSS)-induced colitis can reduce detrimental impact of inflammatory bowel disease.
Biochem/physiol Actions
Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by Homosapiens. DL-α-Tocopherol acetate can inhibit oxidation of linoleate.
α-Tocopherol is also known as a radical-chain breaker due to its anti-oxidant property.
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Storage Class
10 - Combustible liquids
flash_point_f
No data available
flash_point_c
No data available
ppe
Eyeshields, Gloves
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S Grossman et al.
The International journal of biochemistry, 16(3), 281-289 (1984-01-01)
The formation of alpha-tocopherol--lipoxygenase complex was elucidated using immobilized affinity purified soybean lipoxygenase and [D-3H]alpha-tocopherol. The alpha-tocopherol--lipoxygenase complex did not dissociate on addition of linoleic acid. Iodoacetate modified immobilized lipoxygenase did not form the complex with alpha-tocopherol. Lipoxygenase attached to
Julie Carrier et al.
The Journal of nutrition, 132(10), 3146-3150 (2002-10-09)
Inflammatory bowel disease is often associated with iron deficiency anemia and oral iron supplementation may be required. However, iron may increase oxidative stress through the Fenton reaction and thus exacerbate the disease. This study was designed to determine in rats
alpha-Tocopherol stereoisomers
Jensen S K and Lauridsen C
Vitamins and Hormones, 76(3), 281-308 (2007)