B4184
Brij® L23 solution
30 % (w/v) in H2O
Synonym(s):
Brij® 35 solution, C12E23, Polyoxyethylene (23) lauryl ether
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About This Item
CAS Number:
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161900
MDL number:
biological source
synthetic
Quality Level
description
non-ionic
form
liquid
mol wt
~1198.0 g/mol
concentration
30 % (w/v) in H2O
aggregation number
40
CMC
91 μM
transition temp
cloud point ≥100 °C
solubility
water: soluble
HLB
16.9
application(s)
advanced drug delivery
SMILES string
CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChI
1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3
InChI key
IEQAICDLOKRSRL-UHFFFAOYSA-N
General description
Brij® L23, also known as Polyoxyethylene (23) lauryl ether, is an ethoxylated fatty alcohol derived from lauryl alcohol. It serves as a valuable non-ionic detergent widely utilized in biochemical studies. This versatile compound is particularly well-suited for protein solubilization and membrane protein isolation, making it a key component in various biochemical assays. Brij® L23′s non-ionic nature and unique properties also position it as an essential detergent for protein extraction and cell permeabilization, facilitating a broad spectrum of research in the same. Further, its use is instrumental in preserving the structural integrity and functionality of proteins, contributing significantly to studies involving proteins and their interactions in the area of biochemical research.
Application
Brij® L23 solution has been used:
- as a supplement of De Man, Rogosa, Sharpe (MRS) broth for monitoring bacteriocin production by lactic acid bacteria(66)
- as a component of developing buffer for the incubation of zymogram gel for metalloproteinase quantification(67)
- as a component of activation buffer for recombinant human hepsin(68)
Biochem/physiol Actions
Brij® L23 solution is a surfactant and is used in the nanoparticle preparation by microemulsion method.
Features and Benefits
High-purity product ideal for biochemical research applications
Packaging
Some bottles may appear indented due to the packaging process. This does not affect product integrity or quality.
Preparation Note
In the event that material is in the gel phase at room temperature, the customer should heat the material to a temperature range of greater than 35°C and less than 60°C, and stir the solution for approximately 15 minutes before use.
Other Notes
For additional information on our range of Biochemicals, please complete this form.
Legal Information
Brij is a registered trademark of Croda International PLC
flash_point_c
Not applicable
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Eye Irrit. 2
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
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Guillaume Morin et al.
Nutrients, 11(9) (2019-09-06)
Peroxides contaminating parenteral nutrition (PN) limit the use of methionine as a precursor of cysteine. Thus, PN causes a cysteine deficiency, characterized by low levels of glutathione, the main molecule used in peroxide detoxification, and limited growth in individuals receiving
Reverse microemulsion synthesis of CeO2 nanopowder using polyoxyethylene (23) lauryl ether as a surfactant
Pournajaf R, et al.
Ceramics International, 40(6), 8687-8692 (2014)
Sabrina G Fabi et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 38(7 Pt 2), 1112-1127 (2012-01-25)
The aged hand is characterized by cutaneous and dermal atrophy, with deep intermetacarpal spaces, prominent bones and tendons, and bulging reticular veins. Epidermal changes include solar lentigines, seborrheic keratoses, actinic keratoses, skin laxity, rhytides, tactile roughness, and telangiectasia. A Medline