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Merck

D9684

Dextromethorphan hydrobromide

meets USP testing specifications

Synonym(s):

Dextromethorphan hydrobromide monohydrate, (9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide

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About This Item

Empirical Formula (Hill Notation):
C18H25NO · HBr · H2O
CAS Number:
Molecular Weight:
370.32
UNSPSC Code:
41116107
NACRES:
NA.21
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6453793
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Quality Level

agency

USP/NF, meets USP testing specifications

assay

98.0-102.0% anhydrous basis

form

solid

SMILES string

Br[H].[H]O[H].[H][C@]12CCCC[C@]13CCN(C)[C@H]2Cc4ccc(OC)cc34

InChI

1S/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17+,18+;;/m1../s1

InChI key

STTADZBLEUMJRG-IKNOHUQMSA-N

Gene Information



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pictograms

Skull and crossbonesEnvironment

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Shinn-Jong Jiang et al.
Microcirculation (New York, N.Y. : 1994), 20(2), 190-201 (2012-11-13)
This study examines the effect of Dextromethorphan (d-3-methoxy-17-methylmorphinan; DXM), a commonly used cough-suppressing drug, on the expression of VCAM-1 and ICAM-1 in human umbilical vein endothelial cells (HUVECs) stimulated with lipopolysaccharide (LPS). The effect of DXM on expression of cell
Ewa Tomczak et al.
Archiwum medycyny sadowej i kryminologii, 62(3), 197-202 (2013-05-09)
The study highlighted the problem of intoxication using substances and/or preparations, to which nowadays young people have unrestricted access. Based on the case developed in the Department of Forensic Medicine of the Medical University of Gdansk, our team members were
Fixed drug eruption due to dextromethorphan with tolerance to other opioids.
G Davila-Fernández et al.
Journal of investigational allergology & clinical immunology, 23(4), 281-282 (2013-08-24)