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Merck

R7635

Ronidazole

analytical standard

Synonym(s):

1-Methyl-2-(carbamoyloxymethyl)-5-nitroimidazole

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About This Item

Empirical Formula (Hill Notation):
C6H8N4O4
CAS Number:
Molecular Weight:
200.15
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
231-675-1
MDL number:
Technical Service
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grade

analytical standard

Quality Level

assay

≥95%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

−20°C

SMILES string

Cn1c(COC(N)=O)ncc1N(=O)=O

InChI

1S/C6H8N4O4/c1-9-4(3-14-6(7)11)8-2-5(9)10(12)13/h2H,3H2,1H3,(H2,7,11)

InChI key

PQFRTXSWDXZRRS-UHFFFAOYSA-N

General description

Ronidazole is a nitroimidazole compound, commonly used as antiprotozoal and antibacterial agent.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Ronidazole may be used as a reference standard in the determination of the analyte in poultry muscle and eggs using high-performance liquid chromatography with ultraviolet detection and confirmatory analysis by atmospheric pressure chemical ionization-mass spectrometry.


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Synthesis and antiprotozoal activity of 1-(3-chloro-2-hydroxypropyl)-substituted nitroimidazoles.
Hoffer Max and Grunberg E
Journal of Medicinal Chemistry, 17(9), 1019-1020 (1974)
Elizabeth J Kather et al.
Journal of veterinary internal medicine, 21(5), 966-970 (2007-10-18)
The nitroimidazole, ronidazole, has been demonstrated to have in vitro and in vivo activity against the protozoan Tritrichomonas foetus in cats. The purpose of this study was to evaluate the in vitro susceptibility of feline T. foetus isolates obtained from
I Burgener et al.
Schweizer Archiv fur Tierheilkunde, 151(8), 383-389 (2009-08-05)
Recent reports identified Tritrichomonas fetus, the causative agent of bovine trichomonosis, in cats with large-bowel diarrhea in the US. Between July 2007 and August 2008, a total of 105 Swiss cats were tested for T. fetus with the InPouchTM culture