T5428
Tetramethylrhodamine methyl ester perchlorate
≥95% purity, powder
Synonym(s):
TMRM
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About This Item
Linear Formula:
C25H25N2O3 · ClO4
CAS Number:
Molecular Weight:
500.93
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
7162165
Product Name
Tetramethylrhodamine methyl ester perchlorate, ≥95%
Quality Level
assay
≥95%
form
powder
composition
Carbon: 57.5-62.4%
Nitrogen: 5.3-5.9%
technique(s)
titration: suitable
color
dark green
solubility
methanol: 5 mg/mL, clear
εmax
>95000 at 546-552 nm in methanol
fluorescence
λem 573 nm in methanol
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
SMILES string
[O-]Cl(=O)(=O)=O.COC(=O)c1ccccc1C2=C3C=C\C(C=C3Oc4cc(ccc24)N(C)C)=[N+](\C)C
InChI
1S/C25H25N2O3.ClHO4/c1-26(2)16-10-12-20-22(14-16)30-23-15-17(27(3)4)11-13-21(23)24(20)18-8-6-7-9-19(18)25(28)29-5;2-1(3,4)5/h6-15H,1-5H3;(H,2,3,4,5)/q+1;/p-1
InChI key
PFYWPQMAWCYNGW-UHFFFAOYSA-M
General description
Tetramethylrhodamine methyl ester perchlorate (TMRM) is a membrane-permeant, cationic, fluorescent dye that can label mitochondria and mark embryonic stem cell/induced pluripotent stem cell-derived cardiomyocytes. It is useful for the isolation of mature cardiomyocytes.
Application
Tetramethylrhodamine methyl ester perchlorate (TMRM) has been used as a sensitive probe for the detection of mitochondrial membrane potential.
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Kaytee L
PLoS ONE (2016)
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Molecular systems biology, 13(10), 949-949 (2017-10-25)
Histone deacetylases have central functions in regulating stress defenses and development in plants. However, the knowledge about the deacetylase functions is largely limited to histones, although these enzymes were found in diverse subcellular compartments. In this study, we determined the
Yuejiao Ma et al.
Journal of cell science, 132(15) (2019-07-11)
Mitochondrial remodelling is a central feature of stem cell differentiation. However, little is known about the regulatory mechanisms during these processes. Previously, we found that a pharmacological inhibitor of glycogen synthase kinase-3α and -3β, CHIR-99021, initiates human adipose stem cell