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A3785

5-Aminolevulinic acid hydrochloride

Name: 5-Aminolevulinic acid hydrochloride
Brand: SIGMA

≥98%, suitable for ligand binding assays

Synonym(s):

δ-Aminolevulinic acid hydrochloride, 5-Amino-4-oxopentanoic acid hydrochloride, 5-Aminolaevulinic acid hydrochloride, ALA

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About This Item

Linear Formula:

NH₂CH₂C(O)CH₂CH₂COOH · HCl

CAS Number:

5451-09-2

Molecular Weight:

167.59

NACRES:

NA.26

PubChem Substance ID:

24890811

UNSPSC Code:

12352209

EC Number:

226-679-5

MDL number:

MFCD00012869

Beilstein/REAXYS Number:

3690651

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Properties

Product Name

5-Aminolevulinic acid hydrochloride, ≥98%

Quality Segment

300

assay

≥98%

form

powder

technique(s)

ligand binding assay: suitable

mp

150 °C

storage temp.

−20°C

SMILES string

Cl[H].NCC(=O)CCC(O)=O

InChI

1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H

InChI key

ZLHFONARZHCSET-UHFFFAOYSA-N

Description

Application

5-Aminolevulinic acid hydrochloride has been used to activate or inhibit heme biosynthesis in HeLa and K562 cell lines. It has also been used in photodynamic therapy for A431 tumor bearing mice.

Biochem/physiol Actions

Intermediate in heme biosynthesis.

5-Aminolevulinic acid (5-ALA) is an intermediate in heme biosynthesis and is useful in cancer treatment. It is a non-protein amino acid. 5-ALA also has applications in the field of agriculture. It is being studied as an inducing reagent for protoporphyrin IX (PPIX) dependent fluorescence diagnosis of metastatic lymph nodes. 5-ALA is used for photodynamic therapy of diseases, such as Paget′s disease and HPV infection-associated cervical condylomata acuminata.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

0000521972

0000505945

0000505909

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