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Merck

A9795

Adenine hydrochloride hydrate

powder, BioReagent, suitable for cell culture

Synonym(s):

6-Aminopurine hydrochloride hydrate

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About This Item

Empirical Formula (Hill Notation):
C5H5N5 · HCl · xH2O
CAS Number:
Molecular Weight:
171.59 (anhydrous basis)
NACRES:
NA.75
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:
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biological source

synthetic (organic)

Quality Level

product line

BioReagent

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 50 mg/mL

SMILES string

O.Cl.Nc1ncnc2[nH]cnc12

InChI

1S/C5H5N5.ClH.H2O/c6-4-3-5(9-1-7-3)10-2-8-4;;/h1-2H,(H3,6,7,8,9,10);1H;1H2

InChI key

MYRDTAUFFBYTHA-UHFFFAOYSA-N

Application

Adenine hydrochloride hydrate has been used:
  • As a component of FAD cell culture media
  • In maintaining organotypic cultures for recreating stratified epithelium from primary cell cultures
  • In limbal-corneal epithelial culturing and keratinocytes



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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Vitronectin supports migratory responses of corneal epithelial cells to substrate bound IGF-I and HGF, and facilitates serum-free cultivation
Ainscough SL, et al.
Experimental Eye Research, 83(6), 1505-1514 (2006)
Functional investigations of keratinocyte stem cells and progenitors at a single-cell level using multiparallel clonal microcultures
Epidem. Inf., 83(6), 13-23 (2010)
Three-dimensional organotypic culture of stratified epithelia
Rhim Andrew D and Rustgi Anil K
Cold Spring Harbor Protocols, 2015(4) (2015)