C1506
Cytidine 5′-triphosphate disodium salt
≥95%, P2X4 purinergic receptor agonist, powder
Synonym(s):
CTP
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About This Item
Empirical Formula (Hill Notation):
C9H14N3Na2O14P3
CAS Number:
Molecular Weight:
527.12
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
252-849-3
MDL number:
Product Name
Cytidine 5′-triphosphate disodium salt, ≥95%
Quality Level
assay
≥95%
form
powder
storage temp.
−20°C
SMILES string
[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O
InChI
1S/C9H16N3O14P3.2Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1
InChI key
NFQMDTRPCFJJND-WFIJOQBCSA-L
General description
Cytidine 5′-triphosphate is a nucleoside triphosphate with a pyrimidine ring. It is present in RNA.
Application
Cytidine 5′-triphosphate disodium salt has been used:
- for the conversion of adenosine monophosphate (AMP) to adenosine diphosphate (ADP) in luminometry analysis
- in the preparation of ribonucleotide 5′-triphosphate precursors stocks for large-scale RNA synthesis
- to perform in vitro transcription
Biochem/physiol Actions
Cytidine 5′-triphosphate (CTP) prevents the action of aspartate carbamoyltransferase. This enzyme participates in pyrimidine biosynthesis. Like adenosine triphosphate (ATP), CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.
P2X4 purinergic receptor agonist.
Features and Benefits
This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
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Determining structures of RNA aptamers and riboswitches by X-ray crystallography
Nucleosides, nucleotides & nucleic acids, 135-163 (2009)
Andrea L Edwards et al.
Methods in molecular biology (Clifton, N.J.), 535, 135-163 (2009-04-21)
Structural biology plays a central role in gaining a full understanding of the myriad roles of RNA in biology. In recent years, innovative approaches in RNA purification and crystallographic methods have lead to the visualization of an increasing number of
Secretion From Dense Granules
Platelets and megakaryocytes, 83-93 (2004)