G5131
Guanosine 5′-diphospho-D-mannose sodium salt from Saccharomyces cerevisiae
Type I, ≥97% (HPLC)
Synonym(s):
GDP-Man, GDP-mannose
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About This Item
Linear Formula:
C16H23N5O16P2Na2
CAS Number:
Molecular Weight:
649.30
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
Assay:
≥97% (HPLC)
SMILES string
[Na].NC1=NC(=O)c2ncn(C3OC(COP(O)(=O)OP(O)(=O)OC4OC(CO)C(O)C(O)C4O)C(O)C3O)c2N1
InChI
1S/C16H25N5O16P2.Na.H/c17-16-19-12-6(13(28)20-16)18-3-21(12)14-10(26)8(24)5(34-14)2-33-38(29,30)37-39(31,32)36-15-11(27)9(25)7(23)4(1-22)35-15;;/h3-5,7-11,14-15,22-27H,1-2H2,(H,29,30)(H,31,32)(H3,17,19,20,28);;
InChI key
MEXITZOHWLXZKR-UHFFFAOYSA-N
type
Type I
assay
≥97% (HPLC)
storage temp.
−20°C
Quality Level
General description
Guanosine 5′-diphospho-D-mannose (GDP-D-mannose) is present in high cytosolic levels in Saccharomyces cerevisiae. It is crucial for protein mannosylation. GDP-D-mannose is an important precursor to produce GDP-l-fucose.
Application
Guanosine 5′-diphospho-D-mannose sodium salt from Saccharomyces cerevisiae has been used as a nucleotide sugar in transglycosylation enzymatic assay and hydrolysis based catalytic reactions with S-glycosyltransferases (SunS).
Guanosine 5′-diphospho-D-mannose sodium salt has been used as a component of ATP regeneration system for in vitro vesicle formation from Saccharomyces cerevisiae microsomes. It has also been used as a component of the buffer for mannosyl transferase activity assay.
Biochem/physiol Actions
Guanosine diphosphate mannose (GDP-mannose) is a nucleotide sugar substrate for glycosyltransferase (mannosylation) reactions mediated by mannosyltransferases.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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