N1377
4-Nitrophenyl α-D-glucopyranoside
chromogenic, ≥99%, powder or crystals
Synonym(s):
p-Nitrophenyl α-D-glucopyranoside
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About This Item
Empirical Formula (Hill Notation):
C12H15NO8
CAS Number:
Molecular Weight:
301.25
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
223-189-3
MDL number:
Beilstein/REAXYS Number:
92212
Product Name
4-Nitrophenyl α-D-glucopyranoside, ≥99%
Quality Level
assay
≥99%
form
powder or crystals
solubility
methanol: 20 mg/mL, clear to very slightly hazy, colorless to greenish-yellow
storage temp.
−20°C
SMILES string
OC[C@H]1O[C@H](Oc2ccc(cc2)[N+]([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11-,12+/m1/s1
InChI key
IFBHRQDFSNCLOZ-ZIQFBCGOSA-N
Application
4-Nitrophenyl ǥ-D-glucopyranoside has been used as a substrate in an ǥ-glucosidase inhibition assay.
Biochem/physiol Actions
4-Nitrophenyl ǥ-D-glucopyranoside serves as a substrate for glycosidases. Upon cleavage, the substrate is converted to a yellow-colored product.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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P S Unnikrishnan et al.
Pharmacognosy magazine, 11(Suppl 4), S511-S515 (2016-03-26)
In the continuing search for safe and efficient antidiabetic drug, marine algae become important source which provide several compounds of immense therapeutic potential. Alpha-amylase, alpha-glucosidase inhibitors, and antioxidant compounds are known to manage diabetes and have received much attention recently.
Sajjad Esmaeili et al.
Bioorganic chemistry, 88, 102972-102972 (2019-05-13)
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Faryal Chaudhry et al.
Bioorganic chemistry, 82, 267-273 (2018-11-06)
Herein, substituted imidazole-pyrazole hybrids (2a-2n) were prepared via a multi component reaction employing pyrazole-4-carbaldehydes (1a-1d), ammonium acetate, benzil and arylamines as reactants. All the new compounds were characterized through their spectral and elemental analyses. Further these compounds were tested against