P2870
Pristane
synthetic, ≥98% (GC)
Synonym(s):
Norphytane, 2,6,10,14-Tetramethylpentadecane
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About This Item
Linear Formula:
(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)(CH2)3CH(CH3)2
CAS Number:
Molecular Weight:
268.52
UNSPSC Code:
12352001
NACRES:
NA.25
PubChem Substance ID:
EC Number:
217-650-8
Beilstein/REAXYS Number:
1720538
MDL number:
biological source
synthetic
Quality Level
assay
≥98% (GC)
form
liquid
mol wt
268.5
storage condition
(tightly closed)
color
colorless
refractive index
n20/D 1.438 (lit.)
bp
68 °C/0.001 mmHg (lit.)
solubility
hexane: miscible 10 % (v/v)
density
0.783 g/mL at 20 °C (lit.)
storage temp.
room temp
SMILES string
CC(C)CCCC(C)CCCC(C)CCCC(C)C
InChI
1S/C19H40/c1-16(2)10-7-12-18(5)14-9-15-19(6)13-8-11-17(3)4/h16-19H,7-15H2,1-6H3
InChI key
XOJVVFBFDXDTEG-UHFFFAOYSA-N
General description
Pristane, also known as norphytane, is a saturated norterpenoid alkane derived from phytane. Its immunological properties are valuable for various applications, serving as an inflammation-inducing agent in tumorigenesis and autoimmune disease induction, facilitating research on conditions like rheumatoid arthritis and lupus. Pristane′s diverse applications span acting as an immunological adjuvant, inducing autoimmune diseases, facilitating monoclonal antibody production, and serving as an energy source, making it a valuable asset in biochemical research, cell culture, and molecular biology.
Application
Pristane also acts as an immunological adjuvant for generating monoclonal antibodies in mouse ascites and finds use as a biological marker. Additionally, pristane can also be used as the primary carbon and energy source for the growth of a bacterial strain, coryneform soil isolate. Its distinctive ability to induce plasmacytomas is particularly valuable for studying B-cell tumors like Burkitt′s lymphoma.
It is commonly used for priming animals, leading to granulomatous inflammation and disruption of local lymphatic drainage, resulting in increased ascitic yields. It has been used to induce systemic lupus in mice
It is commonly used for priming animals, leading to granulomatous inflammation and disruption of local lymphatic drainage, resulting in increased ascitic yields. It has been used to induce systemic lupus in mice
Pristane has been used as an inflammation-inducing agent, leading to myeloma development in BALB/c strain mice. It has been used as a rheumatoid arthritis-inducing agent in rats.
Features and Benefits
High quality compound suitable for multiple research applications
Other Notes
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Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
10 - Combustible liquids
flash_point_f
>230.0 °F - closed cup
flash_point_c
> 110 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Related Content
Product Information Sheet
Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat.
Tuncel J
PLoS ONE, 11, e0155936-e0155936 (2016)
Marli L Moraes et al.
Journal of nanoscience and nanotechnology, 19(7), 3772-3776 (2019-02-16)
The diagnostics of the autoimmune hemolytic anemia (AIHA), a rare disease caused by autoantibody-induced hemolysis, is still prone to false positives for it is based on visual observation in the so-called Direct Coombs test. In this study, we developed a
Zhenlu Chong et al.
Cellular & molecular immunology, 15(12), 1057-1070 (2018-10-03)
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease, and the pathogenesis of SLE has not been fully elucidated. The E3 ubiquitin ligase FBXW7 has been well characterized in cancer as a tumor suppressor that can promote the ubiquitination and