P3886
Poly-L-proline
suitable for ligand binding assays, Mol wt >30,000
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About This Item
Empirical Formula (Hill Notation):
C5H9NO2
CAS Number:
Molecular Weight:
115.13
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
Product Name
Poly-L-proline, mol wt >30,000
SMILES string
OC(=O)C1CCCN1
InChI
1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)
InChI key
ONIBWKKTOPOVIA-UHFFFAOYSA-N
form
powder
mol wt
>30,000
technique(s)
ligand binding assay: suitable
color
white to light yellow
storage temp.
−20°C
Quality Level
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Analysis Note
Molecular weight based on viscosity.
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Helena Bysell et al.
Langmuir : the ACS journal of surfaces and colloids, 25(1), 522-528 (2008-12-09)
The relative importance of electrostatic and nonelectrostatic interactions in peptide-microgel systems was evaluated by micromanipulator-assisted light microscopy, confocal microscopy, and circular dichroism. For this purpose, the interaction of various homopolypeptides with lightly cross-linked polyelectrolyte gel particles ( approximately 70 microm
Noemi G Mirkin et al.
Biopolymers, 97(10), 789-794 (2012-07-19)
Although subsequent studies have provided extensive support for the 1968 Tiffany and Krimm proposal (Biopolymers 6, 1379) that the polyproline II (PPII) conformation is a significant component of the structure of unordered polypeptide chains, two issues are still not fully
M Rubert et al.
Biomedical materials (Bristol, England), 7(5), 055003-055003 (2012-07-12)
Polyproline-rich synthetic peptides have previously been shown to induce bone formation and mineralization in vitro and to decrease bone resorption in vivo. Alginate hydrogel formulations containing these synthetic peptides (P2, P5, P6) or Emdogain® (EMD) were tested for surface coating of
Madhurima Das et al.
Journal of the American Chemical Society, 134(40), 16536-16539 (2012-09-20)
Proline is incompatible with ideal β-sheet geometry, and the incompatibility gets magnified when Pro assumes the cis peptidyl-prolyl conformation. We show that Gly appears with high propensity at pre-cisPro positions in β-sheets and rescues the β-sheet from severe distortions by
Stefania Conti et al.
Biochimica et biophysica acta, 1828(3), 1066-1074 (2013-01-01)
A proline-rich peptide of 2733Da, isolated from pig parotid granule preparations was tested against different pathogenic fungi. It showed interesting antifungal activity towards a clinical isolate of Cryptococcus neoformans, with an EC(50) of 2.2μM. Neither cytotoxic nor haemolytic effects were
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