P9622
Pristane
synthetic, liquid, sterile-filtered, BioReagent
Synonym(s):
2,6,10,14-Tetramethylpentadecane
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About This Item
Linear Formula:
(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)(CH2)3CH(CH3)2
CAS Number:
Molecular Weight:
268.52
UNSPSC Code:
41116107
NACRES:
NA.75
PubChem Substance ID:
EC Number:
217-650-8
Beilstein/REAXYS Number:
1720538
MDL number:
biological source
synthetic
Quality Level
sterility
sterile-filtered
product line
BioReagent
assay
≥95%
form
liquid
impurities
endotoxin, tested
refractive index
n20/D 1.438 (lit.)
bp
68 °C/0.001 mmHg (lit.)
density
0.783 g/mL at 20 °C (lit.)
SMILES string
CC(C)CCCC(C)CCCC(C)CCCC(C)C
InChI
1S/C19H40/c1-16(2)10-7-12-18(5)14-9-15-19(6)13-8-11-17(3)4/h16-19H,7-15H2,1-6H3
InChI key
XOJVVFBFDXDTEG-UHFFFAOYSA-N
General description
Pristane is a natural saturated terpenoid alkane used in research on the pathogenesis of autoimmune diseases such as arthritis and lupus.
Application
Used to induce disease models for study including arthritis as a non-antigenic arthritogenic adjuvant and plasmacytomas.
Packaging
Packaged in flame sealed ampules.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
>230.0 °F - closed cup
flash_point_c
> 110 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Chen Liu et al.
Journal of autoimmunity, 113, 102498-102498 (2020-06-17)
E proteins, a subset of basic helix-loop-helix (bHLH) proteins, are transcription activators and their functions are inhibited by DNA-binding inhibitor (Id) 1-4. Studies have shown that Treg levels are decreased in Id3 knockout mice. Mice over-expressing Id1 in CD4 T
Yiqin Shi et al.
Journal of immunology (Baltimore, Md. : 1950), 193(10), 5129-5139 (2014-10-05)
Diffuse pulmonary hemorrhage (DPH) is an uncommon but critical complication of systemic lupus erythematosus. Peritoneal administration of 2,6,10,14-tetramethylpentadecane (pristane) can recapitulate a lupus-like syndrome in mice, which can develop into DPH within a few weeks, especially in C57BL/6 mice. Mac-1
Nicholas C Van de Velde et al.
Immunology letters, 130(1-2), 82-88 (2009-12-17)
The major human Fc receptor, huFcgammaRIIa, is implicated in the development of autoimmune arthritis in humans but until recently has not been studied in mouse models. We evaluated potential roles of FcgammaRIIa by using transgenic mice expressing the receptor. We