Skip to Content
Merck

Key Documents

View All Documentation

S1198

Sumatriptan succinate

≥98% (HPLC), solid, 5-HT₁ receptor agonist

Synonym(s):

3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate, GR-43175

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C14H21N3O2S · C4H6O4
CAS Number:
103628-48-4
Molecular Weight:
413.49
UNSPSC Code:
12352200
PubChem Substance ID:
329824466
NACRES:
NA.77
MDL number:
MFCD00902856
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
100
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Sumatriptan succinate, ≥98% (HPLC), solid

Quality Level

100

assay

≥98% (HPLC)

form

solid

color

white to beige

solubility

H2O: >20 mg/mL

originator

GlaxoSmithKline

SMILES string

OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1

InChI

1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)

InChI key

PORMUFZNYQJOEI-UHFFFAOYSA-N

Gene Information

human ... HTR1B(3351), HTR1D(3352)

Biochem/physiol Actions

Sumatriptan succinate has the ability to constrict human cranial arteries. This 5-HT1 receptor agonist can be used to treat migraine.
Sumatriptan succinate is a 5-HT1 serotonin receptor agonist.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Still not finding the right product?

Explore all of our products under Sumatriptan succinate

pictograms

Health hazard
GHS08

signalword

Warning

Hazard Classifications

Aquatic Chronic 3 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000322181
0000322181
0000205788
0000205787

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mucoadhesive bilayered patches for administration of sumatriptan succinate
Shidhaye SS, et al.
Aaps Pharmscitech, 9(3), 909-916 (2008)
Treatment of acute migraine with subcutaneous sumatriptan
Cady RK, et al.
JAMA : The Journal of the American Medical Association, 265(21), 2831-2835 (1991)
Tse-Ming Chou et al.
The journal of headache and pain, 23(1), 157-157 (2022-12-13)
To investigate specific brain regions and neural circuits that are responsible for migraine chronification. We established a mouse model of chronic migraine with intermittent injections of clinically-relevant dose of nitroglycerin (0.1 mg/kg for 9 days) and validated the model with cephalic and
View All Related Papers