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Merck

T9534

Triethanolamine hydrochloride

BioXtra, ≥99.5% (titration)

Synonym(s):

2-[Bis(2-hydroxyethyl)amino]ethanol hydrochloride, TEA-Hydrochloride, trolamine hydrochloride, 2,2′,2′′-Nitrilotriethanol hydrochloride, Tris(2-hydroxyethyl)amine hydrochloride

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About This Item

Linear Formula:
(HOCH2CH2)3N · HCl
CAS Number:
637-39-8
Molecular Weight:
185.65
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
24900428
EC Number:
211-284-2
Beilstein/REAXYS Number:
3909940
MDL number:
MFCD00012596

Product Name

Triethanolamine hydrochloride, BioXtra, ≥99.5% (titration)

InChI key

HHLJUSLZGFYWKW-UHFFFAOYSA-N

InChI

1S/C6H15NO3.ClH/c8-4-1-7(2-5-9)3-6-10;/h8-10H,1-6H2;1H

SMILES string

Cl.OCCN(CCO)CCO

product line

BioXtra

assay

≥99.5% (titration)

form

powder

impurities

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

useful pH range

7.3-8.3

pKa (25 °C)

7.8

mp

177-179 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

application(s)

diagnostic assay manufacturing

Quality Level

200

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Application

Triethanolamine hydrochloride buffer has been used in in-situ mRNA hybridization for acetylation of frozen tissues mounted on slides.

Features and Benefits

  • The BioXtra product line ensures high-quality products for consistent results.
  • A high assay of ≥99.5% guarantees the purity of the product.

General description

Triethanolamine hydrochloride (TEA-HCl) is a salt form of triethanolamine and is commonly used as a buffer substance in biochemistry. It aids in maintaining the stable pH level in a solution during biochemical reactions. TEA-HCL serves as a buffering agent during protein extraction and protein purification. It is commonly used to adjust the pH of buffer solutions in enzyme assays. In addition to its buffering property, it also exhibits surfactant and emulsifying properties and can be used in some cosmetic and personal care products to adjust the pH and improve solubility.

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000503102
0000503102
0000500869
0000500869
0000460166

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Enzymatic catalysis of proton transfer at carbon: activation of triosephosphate isomerase by phosphite dianion
Amyes T L and Richard J P
Biochemistry, 46(19) , 5841-554 (2007)
Assaying plant formate-tetrahydrofolate ligase with monoglutamylated and polyglutamylated substrates using a fluorescence-HPLC based method
Saeheng S and Roje S
Methods in Enzymology, 680 (2022)
The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens
Ishikawa Y, et al.
The Journal of Biological Chemistry, 283(46) , 31584-31590 (2008)
Formulation effects of topical emulsions on transdermal and dermal delivery
Otto A, et al.
International Journal of Cosmetic Science, 31(1) , 1-19 (2009)
Plasticity of endothelial cells: rapid dedifferentiation of freshly isolated high endothelial venule endothelial cells outside the lymphoid tissue microenvironment
Lacorre D A, et al.
Blood, 103(11), 4164- 472 (2004)
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