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Merck

1054000

USP

Benzocaine

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

4-Aminobenzoic acid ethyl ester, Ethyl 4-aminobenzoate

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About This Item

Empirical Formula (Hill Notation):
C9H11NO2
CAS Number:
Molecular Weight:
165.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
638434
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grade

pharmaceutical primary standard

API family

benzocaine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCOC(=O)c1ccc(N)cc1

InChI

1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3

InChI key

BLFLLBZGZJTVJG-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Benzocaine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Benzocaine Lozenges
  • Benzocaine Gel
  • Benzocaine Cream
  • Benzocaine Ointment
  • Benzocaine Topical Aerosol®
  • Benzocaine Otic Solution

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Legal Information

Aerosol is a registered trademark of Cytec Technology Corp.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Stephan Warnke et al.
Journal of the American Chemical Society, 137(12), 4236-4242 (2015-03-12)
The immediate environment of a molecule can have a profound influence on its properties. Benzocaine, the ethyl ester of para-aminobenzoic acid that finds an application as a local anesthetic, is found to adopt in its protonated form at least two
Frédéric G Brunet et al.
BMC evolutionary biology, 15, 22-22 (2015-04-17)
The A Disintegrin-like and Metalloproteinase domain with Thrombospondin-1 motifs (ADAMTS) enzymes comprise 19 mammalian zinc-dependent metalloproteinases (metzincins) with homologues in a wide range of invertebrates. ADAMTS enzymes have a broad range of functions in development and diseases due to their
Melissa Y Cui et al.
Endocrinology, 155(11), 4202-4214 (2014-08-26)
In mammals, leptin acts on leptin receptor (LepR) -expressing neurons in the brain to suppress food intake and stimulate whole-body metabolism. A similar action of leptin on food intake has been reported in the frog Xenopus laevis and in several