574791
Hydroxyapatite
synthetic, 99.8% trace metals basis (excludes Mg)
Synonym(s):
Calcium phosphate tribasic, Calcium hydroxyphosphate, HAp, Hydroxylapatite, Tribasic calcium phosphate
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About This Item
Linear Formula:
[Ca5(OH)(PO4)3]x
CAS Number:
Molecular Weight:
502.31
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
235-330-6
MDL number:
Assay:
99.8% trace metals basis (excludes Mg)
Form:
solid
Quality Level
assay
99.8% trace metals basis (excludes Mg)
form
solid
impurities
≤2500 ppm Trace Metal Analysis
mp
1100 °C (lit.)
application(s)
electroplating
material synthesis precursor
SMILES string
[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O
InChI
1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10
InChI key
XYJRXVWERLGGKC-UHFFFAOYSA-D
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Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Xi Chen et al.
The Journal of biological chemistry, 289(16), 11162-11174 (2014-03-13)
Calcium phosphate precipitates (CPPs) form complexes with DNA, which enter cells via endocytosis. Under this condition CPPs induce autophagy via the canonic autophagy machinery. Here we showed that CPP-induced autophagy was also dependent on endocytosis as the process was significantly
Ehud Segal et al.
PloS one, 4(4), e5233-e5233 (2009-04-22)
There is an immense clinical need for novel therapeutics for the treatment of angiogenesis-dependent calcified neoplasms such as osteosarcomas and bone metastases. We developed a new therapeutic strategy to target bone metastases and calcified neoplasms using combined polymer-bound angiogenesis inhibitors.
Layal Safa et al.
Biochimie, 103, 80-88 (2014-04-22)
Replication protein A (RPA) is a single-stranded DNA binding protein that plays an essential role in telomere maintenance. RPA binds to and unfolds G-quadruplex (G4) structures formed in telomeric DNA, thus facilitating lagging strand DNA replication and telomerase activity. To