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Merck

HADK2MAG-61K

MILLIPLEX® Human Adipokine Panel

Configurable Human Adipokine 8-Plex Panel 2

Synonym(s):

adipocyte inflammation marker listing, adipokine assay snapshot, adipokine biomarker profile, adipose tissue cytokine panel, human adipokine assay overview, human adipokine panel summary, human cytokine product info, human metabolic research tool, inflammation and metabolism biomarker kit, multiplex adipokine product sheet

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000
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species reactivity

human

Quality Level

assay range

accuracy: 87%
(IL-8), accuracy: 91%
(TNFα), accuracy: 94%
(Insulin), standard curve range: 0.64-10,000 pg/mL
(IL-8), standard curve range: 0.64-10,000 pg/mL
(NGF), standard curve range: 0.64-10,000 pg/mL
(TNF-α), standard curve range: 0.96-15,000 pg/mL
(IL-6), standard curve range: 1.3-20,000 pg/mL
(IL-1β), standard curve range: 1.3-20,000 pg/mL
(MCP-1), standard curve range: 38-600,000 pg/mL
(Leptin), standard curve range: 9.6-150,000 pg/mL
(HGF), standard curve range: 9.6-150,000 pg/mL
(Insulin), inter-assay cv: <15%
intra-assay cv: <10%
(IL-1β), inter-assay cv: <15%
intra-assay cv: <10%
(IL-6), inter-assay cv: <15%
intra-assay cv: <10%
(IL-8), inter-assay cv: <15%
intra-assay cv: <10%
(Insulin), inter-assay cv: <15%
intra-assay cv: <10%
(Leptin), inter-assay cv: <15%
intra-assay cv: <10%
(MCP-1), inter-assay cv: <15%
intra-assay cv: <10%
(NGF), inter-assay cv: <20%
intra-assay cv: <10%
(TNFα)

technique(s)

multiplexing: suitable

input

serum plasma

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

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General description

Adipokines are signaling proteins secreted by adipose tissue that influence inflammation, metabolism, and energy balance. This set of biomarkers—IL-1β, IL-6, IL-8/CXCL8, Insulin, Leptin, MCP-1/CCL2, NGF, and TNFα—captures the interplay between metabolic regulation and immune response. These analytes are associated with insulin sensitivity, appetite control, inflammatory signaling, and neuroimmune interactions, making them highly relevant for research in obesity, type 2 diabetes, cardiovascular disease, and chronic inflammation.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 8 analytes in human serum or plasma samples.

Analytes included: IL-1β, IL-6, IL-8/CXCL8, Insulin, Leptin, MCP-1/CCL2, NGF, TNFα

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:
  • Targets key adipokines and cytokines involved in metabolic and inflammatory pathways
  • Includes 8 analytes relevant to insulin signaling, immune response, and adipose tissue function
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with human serum and plasma samples
  • Designed for research in obesity, insulin resistance, inflammation, and metabolic syndrome
Benefits:
  • Provides a comprehensive profile of inflammatory and metabolic biomarkers
  • Supports investigation of adipose tissue dysfunction and systemic inflammation
  • Facilitates evaluation of therapeutic interventions in metabolic and endocrine disorders
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for translational and clinical research

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

pictograms

Skull and crossbonesEnvironment

signalword

Danger

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Altered promoter methylation of PDK4, IL1 B, IL6, and TNF after Roux-en Y gastric bypass.
Kirchner, H; Nylen, C; Laber, S; Barres, R; Yan, J; Krook, A; Zierath, JR; Naslund, E
Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery null
Annalisa Berzigotti et al.
Hepatology (Baltimore, Md.), 65(4), 1293-1305 (2016-12-21)
Obesity increases the risk of clinical decompensation in cirrhosis, possibly by increasing portal pressure. Whether weight reduction can be safely achieved through lifestyle (LS) changes (diet and exercise) in overweight/obese patients with cirrhosis, and if weight loss reduces portal pressure
Waist-to-height ratio, waist circumference and BMI as indicators of percentage fat mass and cardiometabolic risk factors in children aged 3-7 years.
Sijtsma, A; Bocca, G; L'abee, C; Liem, ET; Sauer, PJ; Corpeleijn, E
Clinical Nutrition (Edinburgh, Scotland) null
Hwallip Bae et al.
Neuropsychiatric disease and treatment, 10, 2153-2157 (2014-11-25)
The role of neurotrophic factors has been highlighted as a cause of decline in the cognitive function of alcohol-dependent patients. It is known that nerve-growth factor (NGF), one of the neurotrophins, is related to the growth and differentiation of nerve
Racial differences in HbA1c: a cross-sectional analysis of a Brazilian public primary care population.
de Miranda, VA; Cruz Filho, RA; de Oliveira, TS; Moscavitch, SD; Kang, HC; Miranda Chagas et al.
Primary Care Diabetes null

Global Trade Item Number

SKUGTIN
HADK2MAG-61K-0304053252795893
HADK2MAG-61K-0704053252795930
HADK2MAG-61K-0104053252795879
HADK2MAG-61K-0404053252795909
HADK2MAG-61K-0604053252795923
HADK2MAG-61K-0504053252795916
HADK2MAG-61K-0804053252795947
HADK2MAG-61K-0204053252795886

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