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RBN1MAG-31K

MILLIPLEX® Rat Bone Panel 1

Configurable Rat Bone 8-Plex Panel 1

Synonym(s):

Rat bone remodeling panel, bone turnover biomarkers in rats, rat endocrine bone panel, rat mineral metabolism multiplex, rat skeletal hormone assay

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Product Name

MILLIPLEX® Rat Bone Panel 1,

Quality Level

200

species reactivity

rat

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 88-105%, sensitivity: 0.8-42.2 pg/mL, standard curve range: 0.4-1,500 pg/mL
(PTH), standard curve range: 10-40,000 pg/mL
(ACTH and OPG), standard curve range: 12-50,000 pg/mL
(DKK-1), standard curve range: 22-90,000 pg/mL
(FGF-23), standard curve range: 31-125,000 pg/mL
(Insulin), standard curve range: 5-20,000 pg/mL
(SOST), standard curve range: 7-30,000 pg/mL
(Leptin)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

ACTH, insulin, and leptin regulate endocrine and metabolic activity, while DKK1, FGF-23, OPG, PTH, and sclerostin are key modulators of bone formation, resorption, and mineral homeostasis. Together, these biomarkers provide insight into skeletal health and endocrine-bone interactions in rat models.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 8 analytes in rat serum or plasma samples.

Analytes Included: ACTH, DKK1, FGF-23, Insulin, Leptin, Osteoprotegerin (OPG), PTH, Sclerostin (SOST)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:

  • Multiplex detection of 8 bone and endocrine biomarkers in one assay
  • Magnetic bead-based format for efficient and reproducible processing
  • Compatible with rat serum and plasma
  • High sensitivity for low-abundance targets
Benefits:

  • Saves time and sample volume through multiplexing
  • Reduces assay variability and improves data quality
  • Enables comprehensive profiling of bone and endocrine biomarkers
  • Supports research in skeletal health, bone remodeling, and mineral balance

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cidália Pereira et al.
Nutrients, 11(10) (2019-10-03)
Bone mineral density (BMD) and microstructure depend on estrogens and diet. We assessed the impact of natural mineral-rich water ingestion on distal femur of fructose-fed estrogen-deficient female Sprague Dawley rats. Ovariectomized rats drank tap or mineral-rich waters, with or without
Sok Kuan Wong et al.
International journal of environmental research and public health, 16(18) (2019-09-12)
A positive association between metabolic syndrome (MetS) and osteoporosis has been demonstrated in previous animal studies. The mechanisms of MetS in orchestrating the bone remodelling process have traditionally focused on the interactions between mature osteoblasts and osteoclasts, while the role
Jennifer M Rojas et al.
Toxicologic pathology, 46(7), 777-798 (2018-10-23)
The obese rodent serves as an indispensable tool for proof-of-concept efficacy and mode-of-action pharmacology studies. Yet the utility of this disease model as an adjunct to the conventional healthy animal in the nonclinical safety evaluation of anti-obesity pharmacotherapies has not
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Global Trade Item Number

SKUGTIN
RBN1MAG-31K-0404053252922787
RBN1MAG-31K-0304053252922770
RBN1MAG-31K-0604053252922800
RBN1MAG-31K-0504053252922794
RBN1MAG-31K-0104053252955204
RBN1MAG-31K-0204053252922763
RBN1MAG-31K-0704053252922817
RBN1MAG-31K-0804053252922824